Regeneration of Toxigenic Pasteurella Multocida-induced Severe Turbinate Atrophy in Pigs Detected by Computed Tomography26 November 2013
Using the technique, computer tomography, researchers in Hungary have found that even quite severe damage to the turbinate bones in the nose of pigs with atrophic rhinitis may be repaired by the time the pigs are slaughtered.
Atrophic rhinitis is a widely prevalent infectious disease of swine caused by Bordetella bronchiseptica and Pasteurella multocida, according to Tibor Magyar from the Hungarian Academy of Sciences in Budapest and co-authors there and from Kaposvár University.
In a paper in BMC Veterinary Research, they explain that the course of the disease is considered to be different depending on the principal aetiological agents distinguishing B. bronchiseptica-induced non-progressive and toxigenic P. multocida produced progressive forms.
In order to compare the pathological events of the two forms of the disease, the development of nasal lesions has longitudinally been studied in pigs infected by either B. bronchiseptica alone or B. bronchiseptica and toxigenic P. multocida together using computed tomography to visualise the nasal structures.
B. bronchiseptica infection alone caused moderately severe nasal turbinate atrophy and these lesions completely regenerated by the time of slaughter.
Unexpectedly, Magyar and co-authors note, complete regeneration of the bony structures of the nasal cavity was also observed in pigs infected by B. bronchiseptica and toxigenic P. multocida together in spite of seeing severe turbinate atrophy in most of the infected animals around the age of six weeks.
They concluded that B. bronchiseptica mono-infection has been confirmed to cause only mild to moderate and transient lesions, at least in high health status pigs. Even severe turbinate atrophy induced by B. bronchiseptica and toxigenic P. multocida combined infection is able to be reorganised to their normal anatomical structure.
Computed tomography has further been verified to be a useful tool to examine the pathological events of atrophic rhinitis in a longitudinal manner, added the researchers.
Magyar T., T. Donkó, I. Repa and M. Kovács. 2013. Regeneration of toxigenic Pasteurella multocida induced severe turbinate atrophy in pigs detected by computed tomography. BMC Veterinary Research. 9:222. doi:10.1186/1746-6148-9-222