Pharmacokinetic and Pharmacodynamic Relationships of Tiamulin (Denagard®) for Enteric and Respiratory Infections in Pigs
Pharmacokinetic (PK) and pharmacodynamic (PD) integration has become one of the cornerstones for understanding how antibiotics work against bacteria, according to Novartis Animal Health.

Take Control of Ileitis with Denagard
One of the most prevalent swine diseases in the US, ileitis infects roughly 75 per cent of large herds and nearly all US pigs have been exposed to Lawsonia intracellularis, the bacteria that causes ileitis, according to Novartis Animal Healt...

Denagard Performance - Issue 7 - Ileitis in vitro studies
In vitro studies show that Lawsonia intracellularis, the cause of ileitis, is sensitive to Denagard®.

Denagard Performance - Ileitis/Efficacy
Studies show Denagard® is highly effective against ileitis in pigs, according to Novartis Animal Health.

Aetiology, Pathogenesis and Treatment of Ileitis Infections
Porcine Proliferative Enteropathy (ileitis) exists on most farms, according to Novartis Animal Health. Focusing first on the prevalence in Asian countries, this publication continues with the signs of the acute and chronic forms in pigs of different ages...

Ileitis: Make it Disappear in as Little as 10 Days
Denagard has been proven highly reliable for the control of ileitis time after time, according to Novartis Animal Health.

Tiamulin by Injection – PK/PD Relationships with M. hyorhinis and M. hyopneumoniae
A report of a study into the pharmaocokinetic and pharmacodynamic relationship between tiamulin (Denagard) given by injection and Mycoplasma hyorhinis and M. hyopneumoniae, presented by M. Makhanon (Novartis (Thailand) Ltd), D.G.S. Burch...

PK/PD Integration of Tiamulin by Injection against Mycoplasmal Infections of Lung and Joints
A report of a study into the pharmaocokinetic and pharmacodynamic integration of tiamulin (Denagard®) by injection against mycoplasmal infections of the lung and joints, presented by D.G.S. Burch (Octagon Services Ltd, UK) and U. Klein (Novartis Animal...

Antibiotics Improve Nursery Pig Performance and Profit
Adding antibiotics to the nursery diet improved pig performance and economic return, according to research presented at last year's Kansas Swine Day.

Eradication of Swine Dysentery in an Outdoor Breeding Herd and its Production Pyramid
Sow health improved rapidly and clinical signs resolved within a week of instigating the medication programme (Denagard; Novartis Animal Health Inc.) and the pyramid has remained free of dysentery for over 12 months since the end of medication, according...

Pharmacokinetic/Pharmacodynamic Relationships of Valnemulin and Lawsonia intracellularis the Cause of 'Ileitis'
Effective concentrations of valnemulin (Econor®) were achieved in the ileum contents, which inhibited the development of gross lesions of ileitis at 50ppm, according to David Burch (Octagon Services Ltd, UK) and Ulrich Klein (Novartis Animal Health Inc.,...

Management of Pneumo-Enteric Infections and Vector Control
Enteric infections, the efficacy of Denagard and the role of vectors in disease transfer were covered in a Novartis symposium held during the International Pig Veterinary Society (IPVS) Congress 2010, writes Jackie Linden, editor of ThePigSite.

MICs and MBCs of Tiamulin against Actinobacillus pleuropneumoniae (App) in Broth and 100 Per Cent Serum
The mean MBC was only 1.74 times the MIC for tiamulin against App, which is surprising as it is considered primarily a bacteriostatic antibiotic, according to Andrew Pridmore (Don Whitley Scientific Ltd), David Burch (Octagon Services Ltd) and Peter Lees...

Antimicrobials Boost Nursery Pig Performance, Returns
For the overall trial, adding antibiotics to the diet during any phase improved performance and economic returns, according to M.U. Steidinger and colleagues, presenting their paper at the Kansas Swine Day 2009.

Pharmacokinetic / Pharmacodynamic Relationships of Valnemulin (Econor) for Porcine Proliferative Enteropathy 'Ileitis'
By D.G.S. Burch (Octagon Services Ltd) and U. Klein (Novartis Animal Health Inc.)

Pharmacokinetic / Pharmacodynamic Relationships of Tiamulin (Denagard) for Respiratory Infections in Pigs
By D.G.S. Burch (Octagon Services Ltd) and U. Klein (Novartis Animal Health Inc.)

New Ileitis and Colitis Treatment Indications for Denagard Premix
By David G.S. Burch, BVetMed DECPHM MRCVS, Veterinarian, Octagon Services Ltd.

Studies Show Denagard® is Highly Effective Against Ileitis in Swine
By Ulrich Klein Dr.med.vet, International Technical Services Manager, Novartis Animal Health.

PMWS - Controlling Secondary Infections
By David G S Burch BVetMed MRCVS, Octagon Services Ltd - Apart from a high mortality, which may peak in weaners at 35%, what else do we see with PMWS (Post-weaning multisystemic wasting syndrome) and why. As the name of the syndrome describes, the disease...