PROGRESSIS, the advantages clearly demonstrated on the farm

(Fig 1)

(Fig 2)

(Fig 3)

(Fig 4)

ON FARM, THE FOLLOWING OBSERVATIONS WERE ALSO MADE:

• a reduction in the incidence of problems associated with the on-farm adaptation of gilts
• a decrease in the number of cases of post-farrowing fevers in sows

MA 104 cellular culture on Cytodex (x 100,000)

Diagnosis

Vaccination Programme

THE SAFE, SURE SOLUTION TO RESTORE BALANCE TO YOUR HERD?S HEALTH

PROGRESSIS®. Presentation: Each dose of 2 ml contains: Inactivated PRRS virus (European strain): 2.5 log10 IF units, o/w Oily excipient, q.s.2 ml, Gentamicin: traces. Indications for use. Reduction of the reproductive disorders caused by Porcine Reproductive and Respiratory Syndrome virus (European strain) in a contaminated environment: vaccination of sows and gilts reduces the number of early farrowings and the number of stillbirths. Dosage and administration: One dose of 2 ml is administered by deep intramuscular route, in the neck muscles behind the ear, according to the following vaccination scheme: Primary vaccination: Gilts: 2 injections 3-4 weeks apart, at least 3 weeks before mating. Sows: 2 injections 3-4 weeks apart (Vaccination of all the sows of the herd within a short period is recommended). Revaccination: One injection at day 60-70 of gestation, starting with the first pregnancy following primary vaccination. Contra-indications, warnings, etc.: For animal treatment only. There are no known contraindications. Apply the usual aseptic procedures. Vaccinate only healthy animals. Apply the usual procedures for the handling of animals. Vaccination may induce a transient oedema (at most 3 cm) lasting generally less than one week, and small local reactions (granulomas), without any effect on the health and reproductive performance of the animals. Larger reactions (up to 7 cm diameter) have been observed occasionally after frequent repeated revaccination. Vaccination may rarely cause hypersensitivity reactions. In such cases, an appropriate symptomatic treatment should be carried out. No undesirable effect has been observed in trials after the administration of the vaccine in pregnant or lactating animals. No adverse effect on the serological response has been observed when the vaccine is administered simultaneously, but via a separate site, with Merial?s range of inactivated vaccines against porcine parvovirus, swine influenza, and Aujeszky?s disease. It is recommended that no other vaccine should be administered at the same time as the product. Withdrawal period: Zero days. Operator Safety: In case of accidental injection, seek medical advice immediately and show the package insert to the physician. To the user: This product is a mineral oil-based compound. Accidental self-injection may result in severe pain and swelling and could result in the loss of the affected finger or thumb if prompt medical attention is not given. Ensure that the method of restraint, handling and administration, e.g. by the use of guarded needles, minimizes the risk of accidental injection/self injection. If you are accidentally injected with this product, clean and disinfect the wound immediately. Go AT ONCE to the nearest accident and emergency (casualty) department of a hospital and show the information printed below to the doctor (or nurse) on duty. Seek prompt medical advice even if only a very small amount is injected. If pain persists for more than 12 hours after medical examination, seek further medical advice. To the Doctor: Even if very tiny amounts have been injected, accidental injection with this oil-based product is particularly irritating. The accidental injection can cause intense swelling which may, for example, result in ischaemic necrosis and the loss of a digit in exceptional cases. Expert, PROMPT, surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon. Pharmaceutical precautions: Keep out of reach of children. Use immediately after opening. Shake before use. Do not mix with any other medicinal product. Store at 2?C ? 8?C (in a refrigerator), protected from light. Any unused product or waste material should be disposed of in accordance with national requirements. Legal category: POM. Package quantities: Box of 1 bottle of 5 doses. Box of 1 bottle of 25 doses. Further information: In PRRS infected herds, viral infection is heterogeneous and varies over time. In such context, the implementation of a vaccination program is a tool to improve the reproductive parameters and may contribute to the overall disease control in conjunction with sanitary measures. Marketing Authorization Number: Vm 08327/4204

PROGRESSIS is an inactivated PRRS vaccine for breeding sows and gilts. POM PROGRESSIS is available through your veterinary surgeon. Read package insert before use. For further information contact your veterinary surgeon or call MERIAL on FREEPHONE 0800 592699. Or visit our website www.merial.com Merial A.H. Limited, PO Box 327, Harlow, Essex CM19 5TG. ? Registered trademark of Merial. ? Merial 2001. All rights reserved.