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Bulletin No. 18 - Spring 2004
VirologyPMWS-PCV2-PCVD-PDNS
MATEUSEN B, SANCHEZ RE, VAN SOOM A, MEERTS P, MAES DGD, NAUWYNCK HJ
Susceptibility of pig embryos to porcine circovirus type 2 infection.
Theriogenology, 61, 2004, 91-101
The ability of PCV2 to infect embryonic cells of in vivo produced porcine embryos with or without zona pellucida (ZP) was investigated. PCV2 was able to replicate in ZP-free morulae and blastocysts and embryonic cells of more advanced stage of development appeared more susceptible to the virus. By contrast, ZP-intact embryos were resistant to PCV2 infection. However, given the diameter of the ZP channels compared to that of PCV2 particles, the protection provided by the ZP may not be complete.
