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Bulletin No. 18 - Spring 2004Virology
ALLAN G, MCNEILLY F, MEEHAN B, MCNAIR I, ELLIS J, KRAKOWKA S, FOSSUM C, WATTRANG E, WALLGREN P, ADAIR B
Reproduction of post-weaning multisystemic wasting syndrome in pigs experimentally inoculated with a Swedish porcine circovirus 2 isolate.
J Vet Diagn Invest, 15, 2003, 553-560
To date, despite the presence of PCV2 in Swedish swine herds, no cases of PMWS have been reported in Sweden. In order to understand this phenomenon, an isolate of PCV2 obtained from a Swedish pig necropsied in 1993, thus before the beginning of PMWS outbreaks in the USA and in Europe, and that had no clinical disease nor histological lesions, was inoculated to colostrum-deprived (CD) pigs from a Northern Ireland herd. A complete reproduction of PMWS was achieved. As a consequence, the emergence of PMWS is very unlikely to be due to the introduction of a new pathogenic strain and the status of the pigs and their environment are confirmed as critical factors for the expression of PMWS following PCV2 infection.