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Bulletin No. 18 - Spring 2004

Virology

PMWS-PCV2-PCVD-PDNS

MANKERTZ A, ?ALISKAN R, HATTERMANN K, HILLENBRAND B, KURZENDOERFER P, MUELLER B, SCHMITT C, STEINFELDT T
Molecular biology of porcine circovirus: analyses of gene expression and viral replication.
Veterinary Microbiology, 98, 2004, 81-88

Following a description of the genome organization of circoviruses focused on the cap gene and the rep gene, the analysis of the function of the 2 proteins, Rep and Rep', encoded by PCV1 rep gene is reported. A replication assay was performed and showed that PCV1 Rep and Rep' replicated the origin of both PCV1 and PCV2.


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