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Bulletin No. 18 - Spring 2004
VirologyPMWS-PCV2-PCVD-PDNS
ALLAN GM, MCNEILLY F, ELLIS J, KRAKOWKA S, BOTNER A, MCCULLOUGH K, NAUWYNCK H, KENNEDY S, MEEHAN B, CHARREYRE C
PMWS: experimental model and co-infections.
Veterinary Microbiology, 98, 2004, 165-168
The results of experimental infections of gnotobiotic (GN), colostrum-deprived (CD) and colostrum-fed pigs with PVC2 (CF) with PCV2 are reviewed. PMWS was reproduced with the inoculation of PCV2 alone. Co-infections and immunostimulation were demonstrated to increase the severity of the disease, suggesting that PCV2 may take advantage of the presence of an increased actively replicating cell population to replicate.
