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Bulletin No. 17 - Winter 2003
VirologySwine Influenza
VAN REETH K, GREGORY V, HAY A, PENSAERT M
Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes.
Vaccine, 2003, Volume 21, 1375-1381
BO98419
This study completes previous studies carried out by Kriestien Van Reeth et al. on the same subject (cf. bibliographical bulletin, issue n?16), i.e. the effects of infection with H1N1 and/or H3N2 and resulting immunity on the protection against the H1N2 subtype. Dually H1N1/H3N2 infected-immune pigs were shown to develop reliable immunity against H1N2 (disease and virus replication were absent) while Haemagglutinin (HA) are considered as probably not involved in the process of cross-protection whereas internal proteins, which are relatively conserved in the three different subtypes, are highly suspected to be so.
