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Bulletin No. 16 - Fall 2003

Fourth International Symposium on Emerging and Re-emerging Pig diseases

Porcine Reproductive and Respiratory Syndrome (PRRS)

LAGER KM
Porcine reproductive and respiratory syndrome : control and vaccinology.
Proceedings of the 4th International Symposium on Emerging and Re-emerging Pig Diseases, 2003, 29-36

Updated knowledge regarding epidemiology, immunology and vaccinology is presented together with the available strategies of control and prevention. Even if data keep on accumulating, PRRS is still a complex and mysterious disease lacking absolute rules. The part played by indirect transmission still needs further investigations. The mechanisms of immune response are still wooly and genetic diversity of PRRSV associated with the limited or lack of cross-protection hamper control and prevention of the disease. Eradication of PRRS will not occur in an immediate future, a better understanding of the transmission of PRRSV and the development of innovative vaccines thanks to adjuvants (cytokines, immunoactive peptides) or new technologies (DNA, PRRSV-deletion mutant, viral and bacterial-vectored PRRSV genes) are needed.


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