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Bulletin No. 16 - Fall 2003

Bacterology

Mycoplasma hyorhinis

HIN JH, JOO HS, LEE WH, SEOK HB, CALSAMIG M, PIJOAN C, MOLITOR TW
Identification and Characterization of Cytopathogenic Mycoplasma hyorhinis from Swine Farms with a History of Abortions.
Journal of Veterinary Medical Science, 2003, Volume 65, N?4, 501-509

This paper reports the successive steps that led to the identification and characterization of a variant of Mycoplasma hyorhinis as the cytopathic agent isolated from swine farms with recurrent abortion episodes. The use of differential display reverse transcription-polymerase chain reaction (ddRT-PCR) was the first step of the study and allowed to direct the authors towards mycoplasma and then to Mycoplasma hyorhinis. It is the first report within M. hyorhinis species of such a high cytopathogenetic effect on swine tracheal organs. In addition, the unexpected high percentage of similarity between the 5' portion of a gene of M. hyorhinis and 5'untranslated region (UTR) of human prostate tumor inducing gene 1 (PTI-1) suggests that M. hyorhinis might have been related to the evolution of human PTI-1.


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