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Bulletin No. 16 - Fall 2003
BacterologyMycoplasma hyopneumoniae
BURCH DGS
The role of maternally derived antibodies, age and other factors on vaccinal response (the percentage game).
Pig Journal, 2003, Volume 51, June, 242-257
Following an introduction presenting the main features of Mycoplasma hyopneumoniae infection and the effects of passive immunity on vaccinal response, non-specific and specific immunity mechanisms in relation to enzootic pneumonia are reviewed as well as their development in fetus and newborn piglets. The efficacy of various types of vaccines and adjuvants is also discussed. As a conclusion, the author draws up an inventory of the main points concerning M. hyopneumoniae vaccination: maternally derived antibodies (MDA) can have a negative influence on vaccinal response; conversely, age is not a primary factor to consider in terms of vaccination; control of infection may be more easily correlated to surface immunity (IgA) rather than to humoral or cell-mediated immunity (CMI); M. hyopneumoniae vaccines do reduce lung lesions but with pig-to-pig variations.
