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Bulletin No. 19 - Fall 2004

Virology

PMWS-PCV2-PCVD-PDNS

SEGALES J, PINEIRO C, LAMPREAVE F, NOFRARIAS M, MATEU E, CALSAMIGLIA M, ANDRES M, MORALES J, PINEIRO M, DOMINGO M
Haptoglobin and pig-major acute protein are increased in pigs with postweaning multisystemic wasting syndrome (PMWS)
Veterinary Research, 2004, Volume 35, Nº3, 275-282

The impact of PCV2-infection and PMWS on the acute phase protein (APP) profile was studied through the determination of serum concentration level of two major porcine APP, namely haptoglobin (HPT) and pig major phase protein (pig-MAP), by radial immunodiffusion, in conventional pigs originating from PMWS-affected herds with minimal pathogen microbism. A significant increase in APP was observed in PMWS-affected pigs, but not in pigs with subclinical PCV2 infection, when compared to healthy age-matched pigs suggesting that the level of such APP could be a useful tool to establish the health status of PCV2-infected pigs.


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