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Bulletin No. 19 - Fall 2004
18th IPVS Congress, Hamburg, Germany, 2004Porcine Reproductive and Respiratory Syndrome (PRRS)
NILUBOL D, VINCENT A, HARRIS H, THACKER B, THACKER E
Duration and protection of maternally derived antibodies in pigs farrowed from PRRSV-exposed sows following killed PRRSV vaccine administration (part 2)
Proceedings of the 18th IPVS Congress, Hamburg, Germany, 2004 - Volume 1:113
Piglets born of PRRSV-exposed sows vaccinated with a killed vaccine (PRRomiSe®, Intervet) were demonstrated to have an enhanced antibody responses with higher levels of maternally derived antibodies (MDA). The duration and the level of protection provided by such MDA were investigated by heterologous PRRSV challenge at various time points (10, 16 and 24 days of age) and successive RT-PCR for viral RNA and SN and ELISA for antibodies. A lower, but not significant, viral load was only observed in piglets born of vaccinated sows challenged at 10 days of age when compared to piglets born of non-vaccinated sows. Therefore, although the use PRRomiSe® in sows led to higher MDA in their piglets, it hardly resulted in any clear protection against PRRSV.
