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Bulletin No. 19 - Fall 2004
18th IPVS Congress, Hamburg, Germany, 2004Porcine Reproductive and Respiratory Syndrome (PRRS)
JUILLARD V, PIRAS F, ANDREONI C, CHARREYRE C, JOISEL F
PRRS-specific cell response following PRRSV infection and/or vaccination with an inactivated PRRS vaccine: (2) characterization of the PRRSV-specific responding cells
Proceedings of the 18th IPVS Congress, Hamburg, Germany, 2004 - Volume 1:138
Pigs vaccinated with an inactivated PRRSV vaccine (Progressis®, Merial) either before of after challenge with an homologous PRRSV strains were previously shown to both develop a strong PRRSV-specific IFNγ+ T cell response. In this study, the nature of the PRRSV-specific IFNγ+ T cell response induced by various PRRSV immune stimulations (challenge, vaccination/challenge and challenge/vaccination) was investigated. CD4+CD8+ cells and CD8high+ cells were shown to be the two types of T lymphocytes involved in PRRSV-specific IFNγ+ T cell response following PRRSV infection and/or vaccination.
