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Bulletin No. 19 - Fall 2004
18th IPVS Congress, Hamburg, Germany, 2004Porcine parvovirus
JOISEL F, BRUN A
Porcine parvovirus vaccination-challenge experiment using an adjuvanted inactivated combo vaccine: Parvoruvax? (Merial)
Proceedings of the 18th IPVS Congress, Hamburg, Germany, 2004 - Volume 1:430
In order to assess the efficacy of Parvoruvax? (Merial) nine gilts were vaccinated twice at a 3-week interval, mated 3 weeks after the second injection and then challenged at about 40 days of gestation with a field PPV isolate. A non-vaccinated group of sows was kept as control. All sows were euthanized at about 90 days of gestation. Blood samples from the sows and from their fetuses were tested by hemagglutination inhibition (HI) and fetal tissue samples subjected to ELISA for PPV. Non-vaccinated sows had a significantly higher number of mummified fetuses and significantly lower mean number of live fetuses. In addition, 93% of the fetuses recovered from the non-vaccinated sows were found PPV-infected versus only 12% in the vaccinated group. The results of this study further confirm that Parvoruvax? effectively prevents the intrauterine establishment of PPV infection, fetal damage and thus reproductive failure.
