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Bulletin No. 21 - Spring 2005

Virology

International Society for Animal Hygiene ? Saint-Malo - 2004

LOEFFEN W, DE BOER E, KOCH G
Transmission of a highly pathogenic avian influenza virus to swine in the Netherlands.
Proceedings of the International Society for Animal Hygiene, 2004, 329-330

In 2003, a highly pathogenic H7N7 subtype of avian influenza virus caused an influenza outbreak in Dutch avian population. Serological field surveillance showed that H7N7 had achieved infection only in swine herds in close contact with infected poultry (mixed herds with swine and poultry). In addition, SPF pigs were experimentally intranasally or intramuscularly infected with H7N7. None of the experimentally pigs developed clinical signs and all of them resulted seronegative by Np-ELISA one week after inoculation. Further experiments regarding potential pig-to-pig transmission demonstrated that H7N7 was not transmitted from experimentally infected pigs and contact pigs. As long as H7N7 virus does not undergo adaptations in pigs, it will not be able to induce clinical disease or become endemic in the swine population.


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