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Bulletin No. 25 - Summer 2006
VirologyPMWS-PCV2-PCVD-PDNS
BERGER F
La MAP et son virus: le changement dans la continuité [PMWS and its virus: change and continuity].
Porc Magazine, December 2005, N°394, 60-63
A PMWS roundtable organized by Merial is the occasion to draw up the main features of this still disconcerting disease. Pallor, wasting and enlarged lymph nodes are the main clinical signs, together with pneumonia and gastric ulcers. Three elements are necessary to establish a diagnosis of PMWS: wasting, characteristic histological lesions, and detection of PCV2. PCV2 is not sufficient to induce PMWS which requires additional factors such as co-infection with porcine parvovirus or porcine reproductive and respiratory syndrome virus or even immunostimulation. A litter effect was demonstrated: increasing maternal immunity and reducing sow viremia at farrowing contribute to a reduction of PMWS occurrence in piglets. Management practices are another key element to influence PMWS occurrence: strict all-in/all-out procedures (of at least 5 days), low densities of animals and control of secondary infections are considered essential. The control of PMWS could be based on two complementary means: a vaccine could reduce PCV2 circulation and excretion and improved management practices aimed at limiting and homogenizing the circulating pathogens within the same batch and between one batch and another (vaccination, disinfection procedures, all-in/all-out, reduced mixing of piglets).
