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Bulletin No. 26 - Fall 2006
BacterologyEscherichia coli & Clostridium dificile / perfrigens
SONGER JG, UZAL FA
Clostridial enteric infections in pigs.
Journal of Veterinary Diagnostic Investigation, 2005, Volume 17, Nº6, 528-536
The diagnosis of clostridial enteric infection is a several-step process. Clinical signs, gross and histological lesions consistent with clostridial infection should be subsequently confirmed by high loads of a determined species of Clostridium (in most of the cases C. perfringens type-A and C or C. difficile) and the associated toxin. However, in the case of C. perfringens type-A, the intestines of healthy pigs can also contain large amounts of pathogen and its major toxin. At that point, the diagnostic process should include an additional parameter, i.e. the absence of other enteric pathogen. Furthermore, it is noteworthy that a beta2-producing C. perfringens type-A has recently been associated with disease in piglets and other animals.
