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Bulletin No. 28 - Winter 2007

Bacterology

Mycoplasma hyopneumoniae

HALBUR PG, RAPP-GABRIELSON V, HOOVER T, SORNSEN S, YU S, OPRIESSNIG T, STRAIT E, KESL L, TAYLOR L, JOLIE R, THAKER E
Evaluation of Mycoplasma hyopneumoniae vaccination in a M. hyopneumoniae/porcine circovirus type 2 co-infection model.
Proceedings of the 19th IPVS Congress, Copenhagen, Denmark, 2006 - Volume 1:271

The objective of this study was to determine the impact of pig vaccination against Mycoplasma hyopneumoniae when those pigs were infected by M. hyopneumoniae and porcine circovirus type 2 (PCV2). M. hyopneumoniae-negative pigs were selected for the study and vaccinated with either RespiSure®, Competitor A (with oil-based adjuvant) or Competitor B (with aqueous adjuvant) vaccines. A placebo was administered to the last group. All pigs were then infected both with M. hyopneumoniae and PCV2. Clinical signs were monitored. M. hyopneumoniae and PCV2 antibodies were detected with an ELISA test. The results showed that the co-infection lead to the development of more severe clinical signs and of pneumonia but also showed that vaccination against M. hyopneumoniae reduced the severity of the respiratory disease developed by pigs with other agents.


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