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Bulletin No. 29 - Spring 2008

Bacterology

Mycoplasma hyopneumoniae

MEYNS T, DEWULF J, DE KRUIF A, CALUS D, HAESEBROUCK F, MAES D
Comparison of transmission of Mycoplasma hyopneumoniae in vaccinated and non-vaccinated populations.
Vaccine, 2006, Volume 24, Nº49-50, 7081-7086

The purpose of this study was to investigate the effects of vaccination on the transmission of Mycoplasma hyopneumoniae in vaccinated and non-vaccinated pigs. Sixty piglets were selected for the study and randomly allocated to two groups. Group 1 piglets were vaccinated against M. hyopneumoniae and piglets from the other group received a sterile saline solution. Three pigs from each group were then challenged with a virulent M. hyopneumoniae strain and contact piglets were then housed with them. All piglets were monitored throughout the study. Blood samples were regularly collected and tested for M. hyopneumoniae infection. A nested-PCR was carried out after necropsy to confirm the infectious status. The results showed that vaccination tended to slightly reduce the transmission of M. hyopneumoniae between piglets. However, it should be noted that the experimental conditions of the present study were far better than actual field conditions and that the results obtained may therefore be different under field conditions.


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