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Bulletin No. 29 - Spring 2008
VirologySwine Influenza
REETH KV, LABARQUE G, PENSAERT M
Serological profiles after consecutive experimental infections of pigs with European H1N1, H3N2, and H1N2 swine influenza viruses.
Viral Immunology, 2006, Volume 19, Nº3, 373-382
The aim of this study was to investigate the efficacy and reliability of the hemagglutination inhibition (HI) test in the detection of three swine influenza viruses (SIV) subtypes (H1N1, H3N2 and H1N2). The 60 pigs selected for the study were challenged either with all three virus subtypes or with one or two subtypes only. Some of those pigs, which were infection-immune, were then vaccinated against SIV in order to investigate the serological response induced. Blood samples were collected and antibody titers against H1N1, H3N2 and H1N2 were quantified thanks to HI and virus neutralisation tests. The results confirmed that the HI test was indeed a reliable tool to differentiate the three SIV subtypes above-mentioned as long as the SIV vaccination status was known.
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