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Bulletin No. 31 - Fall 2008
BacterologyMycoplasma hyopneumoniae
SIBILA M, NOFRARIAS M, LOPEZ-SORIA S, SEGALES J, VALERO O, ESPINAL A, CALSAMIGLIA M
Chronological study of Mycoplasma hyopneumoniae infection, seroconversion and associated lung lesions in vaccinated and non-vaccinated pigs
Veterinary Microbiology, 2007, Volume 122, 97-107
The objectives of the present study were to investigate Mycoplasma hyopneumoniae infection dynamics with a nested PCR and its serology in pigs from a farm affected by enzootic pneumonia (EP), and to investigate the possible relation between M. hyopneumoniae infection and EP gross and microscopic lung lesions. A total of 542 pigs, previously vaccinated against M. hyopneumoniae infection, were selected for the study and randomly assigned to 3 different groups. Pigs from group 1 received two doses of vaccine during the study, while pigs from Group 2 received only one dose. The third group was used as control group. Nasal swabs and blood samples were collected on a regular basis throughout the experiment. Also regularly, some of the studied pigs were necropsied in order to assess gross and microscopic lung lesions. The results showed that seroconversion occurred earlier in vaccinated pigs and that pigs that were given a double dose of vaccine presented with fewer EP gross lung lesions and a lower prevalence of M. hyopneumoniae in the upper respiratory tract.
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