IPVS 2008: Vaccination against ileitis caused by Lawsonia intracellularis (LI) has been possible in Europe since 2005, when the oral vaccine Enterisol® Ileitis Vet. was introduced. This vaccine has proven to be effective in controlling ileitis and improve production parameters in herds infected with LI. In practice, many herds experience reduced performance from multiple causes. The consequences of ileitis in such herds can be exaggerated by improper management practices such as mixing of pigs with different infection status as it is done in herds with continuous production systems. The present study was designed to examine the effect of vaccination against ileitis on production parameters in continuous managed herds.