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20 mg/ml Solution for Injection for Pigs

Back to Main PageMetacam 20mgs/ml solution for Injection for cattle and pigs
Metacam Injection (2%) is a Non Steroidal Anti-inflammatory Drug (NSAID) licensed for the treatment of Metritis, Mastitis, Agalactiae syndrome (MMA) and lameness in pigs. It is a potent NSAID given as a single injection of 2.0mls/100kg bodyweight by the IM route. It can be repeated after 24 hours if considered clinically necessary. Metacam injection is a potent anti-endotoxic, anti-inflammatory, anti-pyretic and analgesic drug. It controls the pain associated with lameness and leads to the production of more piglets weaned per litter produced by sows affected with MMA.
Back to Main PagePresentation
Each ml of the solution for injection contains 20 mg meloxicam and 150 mg ethanol (as preservative).
Back to Main PageComparative Trials
Comparative field trials prove the outstanding efficacy of Metacamtm
Metacam treatment produced a statistically significant clinical improvement with feed intake and behaviour scores showing significant improvements leading to a quicker return to feed and well-being
Back to Main PageUse
Metacam 20 mg/ml solution is a non-steroidal anti-inflammatory drug (NSAID) for use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation. For adjunctive therapy in the treatment of puerperal septicaemia and toxaemia (mastitis-metritis-agalactia syndrome) with appropriate antibiotic therapy.
Back to Main PageDosage and administration
Single intramuscular injection at a dosage of 0.4 mg meloxicam/kg bodyweight (i.e. 2.0ml/100kg bodyweight) in combination with antibiotic therapy, as appropriate. If required, a second administration of meloxicam can be given after 24 hours.
Back to Main PageContra-indications, warnings, etc
Do not use in animals suffering from impaired hepatic, cardiac or renal function and haemorrhagic disorders, or where there is evidence of ulcerogenic gastro-intestinal lesions or individual hypersensitivity to the product. For the treatment of diarrhoea, do not use in animals less than one week of age.

Do not administer concurrently with glucocorticosteroids, other non-steroidal anti-inflammatory drugs or with anti-coagulant agents.

Avoid use in very severely dehydrated, hypovolaemic or hypotensive animals which require parenteral rehydration, as there may be a potential risk of increased renal toxicity.

Subcutaneous, intramuscular as well as intravenous administration is well tolerated; only a slight transient swelling at the injection site following subcutaneous administration was observed in less than 10% of the cattle treated in clinical studies.

In case of overdosage, symptomatic treatment should be initiated.

Operator warnings

Accidental self-injection may give rise to pain. People with known hypersensitivity to NSAIDs should avoid contact with the veterinary medicinal product.

In case of accidental self-injection, seek medical advice immediately and show the package insert or label to the physician.

Disposal Advice

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

For animal treatment only.

Keep out of reach of children.

Withdrawal Period

Meat and offal – 5 days.
Back to Main PagePharmaceutical precautions
Shelf life of broached vial: 28 days

Do not use after the expiry date stated on the carton and on the bottle.

Avoid introduction of contamination during use.
Back to Main PagePackage quantities
Colourless glass injection vials of 50 ml, sealed with a rubber stopper and aluminium cap.
Back to Main PageFurther information
Pharmacodynamic properties

Meloxicam is a non-steroidal anti inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, anti-exudative, analgesic and antipyretic properties. Meloxicam also has anti-endotoxic properties because it has been shown to inhibit production of thromboxane B2 induced by E. coli endotoxin administration in pigs.

Pharmacokinetic properties:

After two intramuscular doses of 0.4mg meloxicam/kg, a Cmax value of 1.9 µg/ml was reached after 1 hour in pigs.

More than 98% of meloxicam is bound to plasma proteins. The highest meloxicam concentrations are to be found in liver and kidney. Comparatively low concentrations are detectable in skeletal muscle and fat.

Meloxicam is predominately found in plasma. In pigs, bile and urine contain only traces of the parent compound. Meloxicam is metabolised to an alcohol, an acid derivative and to several polar metabolites. All major metabolites have been shown to be pharmacologically inactive.

In pigs, after intramuscular injection, the mean plasma elimination half life is approximately 2.5 hours. Approximately 50% of the administered dose is eliminated via urine and the remainder via faeces.

Back to Main PageMarketing authorisation number
50 ml EU/2/97/004/007
Back to Main PageMarketing Authorisation Holder:
Boehringer Ingelheim Vetmedica GmbH, 55216 Ingelheim am Rhein, Germany

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