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DENAGARD 45% WSG

DENAGARD 45% Water Soluble Powder is indicated for use in the treatment and prevention of bacterial and mycoplasmal infections caused by tiamulin sensitive organisms involving the intestinal and respiratory tracts and joints.



PAGE VERSION: INTERNATIONAL

THIS information is for Non-U.S. residents only (U.S. Residents click here) and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. See full disclaimer below
Denagard® 45% Soluble Powder for Pigs

Product Type

Oral antibiotic intended for preventive and therapeutic use in pigs and poultry.

Description and Composition

DENAGARD 45% WSG is a water soluble granulate formulation containing 45g tiamulin hydrogen fumarate per 100g of products. It is used for medication in drinking water.

Properties

Tiamulin is a bacteriostatic agent, belonging to the group of pleuromutilins and acts at the ribosomal level to inhibit bacterial protein synthesis. It has a wide spectrum of activity but is particularly active against Brachyspira, Lawsonia and Mycoplasma species. Tiamulin belongs to a category of antibiotics which is not used in human medicine.

Indications

Treatment and prevention of Mycoplasma infections (enzootic pneumonia, chronic respiratory disease), pleuropneumonia and porcine respiratory disease complex.

DENAGARD is particularly indicated for the treatment of swine dysentery (B.hyodysenteriae)

Dosage and administration

Pigs:
  • Treatment of swine dysentery: 8.8 mg tiamulin hydrogen fumarate / kg bodyweight for 3-5 consecutive days
  • Treatment of PRDC (porcine respiratory diseases complex): 15 – 20 mg tiamulin hydrogen fumarate / kg bodyweight for 5 – 10 consecutive days
  • Treatment of pleuropneumonia: 20 mg tiamulin hydrogen fumarate / kg bodyweight for 5 consecutive days

Indications

Tiamulin (concentration in water in %)

Product
(in grams)

Water
(in liters)

Treatment
(in days)

Treatment swine dysentery

0.006

1

7.5

3-5

Treatment PRDC

0.012 / 0.018

1

3.75 / 2.5

5 – 10

Treatment pleuropneumonia

0.018

1

2.5

5


Chickens:
  • Prevention of chronic respiratory disease (CRD) and air sacculitis: 12.5 mg tiamulin hydrogen fumarate / kg bodyweight
  • Treatment of chronic respiratory disease (CRD) and air sacculitis: 25 mg tiamulin hydrogen fumarate / kg bodyweight
Turkeys:
  • Prevention of infectious sinusitis and air sacculitis: 12.5 mg tiamulin hydrogen fumarate / kg bodyweight.
  • Treatment of infectious sinusitis and air sacculitis: 25 mg tiamulin hydrogen fumarate / kg bodyweight

Indications

Tiamulin (concentration in water in %)

Product
(in grams)

Water
(in liters)

Treatment
(in days)

Prevention CRD / air sacculitis/ infectious sinusitis

0.0125

1.1

4.0

3 days (1 st week of life); 1-2 days (every 3-4 weeks)

Treatment CRD / air sacculitis/ infectious sinusitis

0.025

1.1

2.0

3 – 5


Withdrawal Periods

Withdrawal periods according to national registrations.

Special Precautions and Warnings

Do not administer ionophore anticoccidials (salinomycin, monensin, narasin) to pigs and poultry receiving therapeutic doses of DENAGARD. Pigs and poultry should not receive products containing ionophores during or for at least seven days before or after treatment with DENAGARD.

Formulations and Packages

DENAGARD 45% Water Soluble Granule
  • Box of 70 x 111,2 g or 55,6 g sachets
  • Box of 10 x 1112 g bags
  • Box of 3 x 5000g bags




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PAGE VERSION: INTERNATIONAL

Product information on this website is for Non-U.S. residents only and is provided by Novartis Animal Health Inc. for general purposes only. Many veterinary products listed are available upon prescription only, and not all such products may be available in all countries. The product information is not intended to provide complete medical information. SHOULD YOUR ANIMAL HAVE A MEDICAL CONDITION, PROMPTLY SEE YOUR OWN VETERINARIAN. WE DO NOT OFFER PERSONALIZED MEDICAL DIAGNOSIS OR ANIMAL-SPECIFIC TREATMENT ADVICE. You should always obtain complete medical information about your veterinary product prescription (including their beneficial medical uses and possible adverse effects) by discussing the appropriate use of any veterinary product directly with the prescribing veterinarian.

Veterinary professionals may obtain complete medical information from the product's information leaflet. Information on these products may vary by country. Animal owners and veterinarians should check with local medical resources and regulatory authorities for information appropriate to their country. In addition, current regulations in many countries limit (or even prohibit in some instances) the ability of Novartis Animal Health Inc. to provide information and/or to respond directly to questions regarding its prescription products. Novartis Animal Health Inc., however, will respond to inquiries from and provide information to your qualified health care professional in accordance with local regulations.
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