In tests conducted by
independent research facilities*,
M+Pac-vaccinated pigs
demonstrated: -- higher antibody
titers -- reduced lung lesion
scores -- less coughing -- higher
cell-mediated immunity (as indicated
by increased white blood cell
activity)
Contains oil-in-water
dual-action adjuvant, Emunade®
for
Faster acting, longer
lasting protection
Less tissue
reaction
Excellent
syringeability
Convenient
administration
Data
on file at Schering-Plough Animal Health Corporation *Veterinary Resources, Inc., ISU
Research Park, Ames, IA Medical Research Institute, Iowa State
University, Ames, IA
General Information
Mycoplasma pneumonia in swine (MPS) or enzootic
pneumonia caused by Mycoplasma hyopneumoniae appears to be one of
the primary pathogens causing Porcine Respiratory Disease Compex
(PRDC). It is probably the most economically significant
disease-associated condition in modern swine production. Losses are
generally associated with a complex interaction between mycoplasma
infections, bacterial infections, and poor management and
environmental conditions.
MPS occurs worldwide. It
generally appears as a chronic, clinically mild, infectious
pneumonia. It is characterized by its ability to become endemic in a
herd and produce a persistent dry, hacking cough, reduced growth
rate, sporadic flare-ups of overt respiratory distress and a high
incidence of lung lesions at slaughter.
MPS has been shown to
predispose swine to pneumonia caused by Pasteurella multocida and
Actinobaccillus (Haemophilus) pleuropneumoniae. Virtually all
naturally occurring cases of MPS are mixed infections involving
mycoplasma, bacteria, viruses, or parasites. Onset of the disease is
generally gradual with the principal clinical sign of a chronic
nonproductive cough. Morbidity is generally high but in the absence
of secondary bacterial infection, mortality remains low. Animals
infected with secondary bacterial invaders may experience
inappetence, labored breathing or “thumping”, increased coughing,
and elevated temperatures. MPS pigs do not appear clinically ill but
do exhibit signs of unthriftiness, unevenness, reduced growth rates,
and stunting.
Indications
For use
as an aid in the prevention of pneumonia caused by Mycoplasma
hyopneumoniae infection in swine. Dosage and Route of Administration
Using aseptic technique, inject 1 ml dose SQ or IM at 7-to-10 days
of age or older. Revaccinate with 1 ml 2 weeks after initial
vaccination. Revaccinate with a single 1 ml dose annually.
Caution
For
veterinary use only. Store at 2º-7ºC (35º-45ºF). Do not freeze. Use
entire contents when first opened. Do not vaccinate within 60 days
before slaughter. Transient local reaction may occur at the
injection site. If allergic response occurs, administer
epinephrine.
Preservatives
Ampicillin, Gentamicin, and
Thimerosal.
Warning
Extreme
caution should be used when injecting any oil emulsion vaccine to
avoid injecting your own finger or hand. Accidental injection can
cause serious local reaction. Contact a physician immediately if
accidental injection occurs.
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