ThePigSite Pig Health
Nipah Virus DiseaseThis is a totally new disease that first became evident in September 1998 in Malaysia. In March 1999 a previously unknown virus was isolated from an adult male who having had contact with pigs died. The virus was identified as a previously unknown paramyxovirus and the disease was called Nipah Disease from the village in Malaysia where it was first identified.
The virus causes illness and death in both humans and pigs.
Symptoms may be mild or severe and include:
- Fever, headaches, encephalitis.
- Drowsiness, confusion leading to coma.
- Respiratory failure.
- High mortality up to 40% reported.
- A few people have shown no symptoms.
- The incubation period is from 7 to 21 days.
- Morbidity is usually high but mortality is low.
- Rapid laboured breathing.
- Very harsh explosive cough.
- In sows disease may be more pronounced with severe breathing difficulties.
- Convulsions, death.
- Mucopurulent discharges from the nose.
Causes / Contributing factors
- Movement of pigs.
- Direct pig to pig contact either by mouth, by the respiratory route or aerosol from urinary excretions.
DiagnosisThis is by serological tests, virus isolation and identification. In infected farms sows show high levels of antibodies and in infected areas antibodies have been widespread in dogs but not in rats.
Management control and preventionThe control programme adopted has been in two phases.
- In 1999 there was a mass culling of pigs in infected areas and severe restrictions on movement of pigs.
- This has been successful in preventing disease spreading to Singapore where many pigs from Malaysia were slaughtered.
- The second phase is the identification of carrier herds and their depopulation.
Further readingFor further more indepth information on Nipah disease, read the following articles below. News on the most recent outbreaks in Malyasia can be found in the latest news archives:
Nipah Virus A thorough article from CIDRAP covering all aspects of the disease. - April 2004
What are Hendra and Nipah viruses? A article from CDC (Centers for Disease Control and Prevention).
Fact sheet from World Health Organization A fact sheet on Nipah and Hendra virus.
The Nipah Virus Outbreak - A Reminder P A Tambyah - Singapore Medical Journal 1999; Vol 40(05):
Lesson to be Learnt from the Nipah Virus Outbreak in Singapore A E Ling - Singapore Medical Journal 1999; Vol 40(05):