Clinical signs

The most striking clinical feature is the swollen red vulva of immature gilts. The other signs are dependent up on the levels present in the feed and the state of pregnancy. The following may be used as guidelines to the symptoms that may be observed.

• Boars - Semen may be affected with feed levels above 30ppm but not fertility. At higher levels poor libido, oedema of the prepuce and loss of hair may occur.
• Gilts (Pre puberty) 1 - 6 months of age - 1 to 5ppm in feed causes swelling and reddening of the vulva and enlargement of the teats and mammary glands. Rectal and vagina prolapses also occur in the young growing stock.
• Gilts (mature) - 1 to 3ppm will cause variable lengths of the oestrus cycle due to retained corpora lutea and infertility.
• Sows - Levels of 5 to 10ppm can cause anoestrus, which may also be associated with pseudo pregnancy due to the retention of corpus luteum. F2 toxin will not normally
• cause abortion however. If sows are exposed during the period of implantation litter size may be reduced. In lactation piglets may develop enlarged vulva.
• Effects on pregnancy - Embryo survival to implantation does not appear to be affected at levels less than 30ppm but above this complete loss between implantation and thirty days occurs followed by pseudo pregnancies. Low levels of 3 to 5ppm do not appear to affect the mid part of pregnancy, but in the latter stages piglet growth in utero is depressed, with weak splay-legged piglets born. Some of these may have enlarged vulvas.
• Effects on lactation - 3 to 5ppm has no effect on lactation but the weaning to service interval may be extended.