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Pig Journal Volume: 66
Publication date: December 2011

Case Studies

UNUSUAL MANIFESTATION OF PORCINE CIRCOVIRUS-ASSOCIATED DISEASE (PCVAD) AMONG VACCINATED GROWER FINISHER PIGS WITH ISOLATION OF PCV2 FROM TISSUES
B.W. STRUGNELL, M.E.C.WHITE, R.J. HIGGINS, G. IBATA, S. GRIERSON, M. BANKS

Abstract
Vaccines against Porcine Circovirus type 2 (PCV2) have recently become available in the UK and have changed the landscape of Porcine Circovirus Associated Disease (PCVAD), resulting in significant improvements in growing pig performance,mortality rates and consequent improved pig welfare in the majority of vaccinated herds. In contrast, this case report describes an acute clinical presentation with high mortality accompanied by necrotic tonsillitis, hepatitis and splenic infarction, attributable to PCVAD, in vaccinated grower pigs soon after entering continuous flow accommodation. The PCV2 virus grew readily in tissue culture but no novel or unique features of the viral genome were detected to account for the unusual clinico-pathological presentation. It was hypothesised that despite PCV2 vaccination, new entrant grower pigs immune status proved inadequate to fully protect against the high natural PCV2 and mixed bacterial challenges in the continuous flow system. PCVAD should be included as an important differential diagnosis for such acute clinical presentations with high mortality which could be mistaken for Notifiable Diseases such as swine fever or Aujeszky’s disease.

 
 
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