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Pig Journal Volume: 52
Publication date: November 2003

Proceedings Section

PHARMACOKINETICS - ANTIMICROBIAL SENSITIVITY AND RESISTANCE
D.G.S. Burch

Abstract
In the UK, approximately 40-45% of the therapeutic use of the 459 tonnes of antimicrobials used are administered to pigs. Much concern has recently been expressed over the development of resistant bacteria in pigs and the possibilities of the spread of antimicrobial resistance to man either by zoonotic pathogens or by bacterial contamination of food. To help the veterinarian and producer choose the antimicrobial more effectively, so that therapeutic response is improved and resistance reduced, the use of pharmacokinetics and pharmacodynamics, in relation to the minimal inhibitory concentrations against various pathogenic bacteria, is discussed and data is presented.

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