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Pig Journal Volume: 55
Publication date: May 2005

Proceedings Section

PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME (PRRS) - IS IT CHANGING IN THE UK?
S.H. Done, T. Drew, C. Gaudie, C. Featherstone, R. Reichel, J-P. Frossard, G. Ibata, D. Westcott, J. Owen, R. Evans and E. Button

Abstract
This paper describes three unusual outbreaks of respiratory or reproductive disease in which there was serological and virological evidence of PRRS infection. The virus was also isolated from tissues or pigs submitted to the regional laboratory. Animals examined had interstitial pneumonia. There was confirmed immunohistochemistry on the lung tissues. Animals examined also had evidence of Post-weaning Multisystemic Wasting Syndrome (PMWS) infection and a wide variety of secondary bacterial infections. Sophisticated sequencing allowed the Open Reading Frame 7 of the virus to be sequenced and it was shown to be around 92-95% similar to the Lelystad virus. It was also less similar to the recent local viruses isolated. The consequences for the immunogenicity and the virulence of the European variety of the virus is unknown. What can be said with certainty is that the virus is changing fairly rapidly and monitoring of the changes is required.

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