CLINICAL COMPARISON OF TISSUE TOLERANCE OF MELOXICAM 20mg INJECTABLE AND FLUNIXIN INJECTABLE IN PIGS
T. Magyan and R. Glavits

Abstract
A total of 32 pigs, equally divided into two treatment groups, were used in this blind, positively controlled, randomised clinical study. Group 1 pigs received meloxicam 20mg injectable solution and Group 2 pigs received flunixin 50mg/ml injectable solution as single intramuscular injections.

Pigs were sacrificed on days 2, 5 and 15 post-injection and gross and histopathological examinations of the injection sites of all animals were performed. Gross examination of injection sites revealed measurable lesions in seven out of sixteen meloxicam-treated pigs and in fifteen out of sixteen flunixin-treated pigs. Histopathological examinations confirmed that lesions were fewer and less severe in pigs treated with meloxicam compared with those treated with flunixin.

The results of this study show that meloxicam administered intra-muscularly will give significantly less severe macroscopic and histopathological lesions than flunixin meglumine solution.

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