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Pig Journal Volume: 60
Publication date: December 2007

Clinical Practice

WHY CHOOSE CHLORTETRACYCLINE (CTC) IN PIGS WITH PORCINE RESPIRATORY DISEASE COMPLEX (PRDC)? A REVIEW
A. Dereu and F. Somers

Abstract
The multiplicity of causal factors including primary and secondary pathogens, and a wide variety of environmental and managemental factors involved in the aetiology of Porcine Respiratory Disease Complex (PRDC) are discussed. Control can be achieved using vaccinations for the component diseases and also strategic antimicrobial therapy. Tetracyclines and particularly chlortetracycline (CTC) in the feed, have been particularly useful in controlling PRDC over the years. Chlortetracycline is more efficacious than either tetracycline or oxytetracycline, with higher bio-availability and plasma concentration peaks.

In two experiments reported in this paper, Aurofac® decreased the number of Mycoplasma organisms in the lungs and also the lung lesions in pigs infected with M. hyopneumoniae and PRRSv. In the second experiment, Aurofac® was used to treat co-infected pigs (PRRS and PCV2) and they had less severe clinical disease when compared with their non-treated counterparts. Aurofac® granulated pre-mix gave a more even distribution than another granulated CTC product and a powder formulation.

Chlortetracycline of high quality that is convenient to use and with a high spectrum of activity against swine pathogens can be useful in treating PRDC.

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