NEONATAL VACCINATION FOR MYCOPLASMA HYOPNEUMONIAE AND POST-WEANING MULTISYSTEMIC WASTING SYNDROME: A FIELD TRIAL
by G.M. Allan, F. McNeilly, I. McNair, M. O?Connor, B. Meehan, D. Gilpin, J. Ellis, H. Townsend, C. Lasagna, G. Boriosi and S. Krakowka

Abstract
A field study on the effects of Mycoplasma hyopneumoniae vaccination of piglets on a farm with a severe post-weaning multisystemic wasting syndrome (PMWS) problem is reported. This farm had suffered >25% losses, for several months prior to initiation of this study. Vaccination of piglets in the first and fourth week of life with a commercial Mycoplasma hyopneumoniae vaccine was initiated on this farm in 1996, 39 months before PMWS problems were seen.
???? Mycoplasma hyopneumoniae vaccination was withdrawn from approximately 50% of the piglets born (n= 696) over a 4 months period and losses due to deaths and wasted pigs in vaccinated and non-vaccinated animals recorded. Immuno-staining of tissue sections from dead pigs for PCV2 antigen and quantitative PCV2 virus isolation studies were carried out on tissues from selected pigs. In non-vaccinated animals, losses due to deaths and wasted pigs were reduced in 4 of the 5 groups studied. PCV2 antigen and infectious virus were demonstrated in association with lesions in the majority of dead and wasted pigs examined in this study.

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