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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
 
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
 
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
 
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Monday, May 01, 2006: Pig Journal Volume: 57, Refereed Section
Post-Weaning Multisystemic Wasting Syndrome: Studies on Disease Progression in Relation to Serum Antibody Levels to Porcine Circovirus Type 2 (PCV2) in Sows and Piglets and PCV2 Viraemia in Young Pigs
F. McNeilly, I. McNair, G. Stewart, G. Allan, L.E. Green, C. Waldner, J. Ellis, D. Armstrong and S. Krakowka
Blood samples were taken from 78 sows and 774 piglets on five farrow-to-finish farms in England. Three of these farms had ongoing outbreaks of Post-weaning Multisystemic Wasting Syndrome (PMWS) and two were unaffected up to, and during, the time of the study. Sows were sampled 7 days prior to farrowing and piglets were sampled within the first 7 days of life. Serum antibody levels to Porcine Circovirus type 2 (PCV2) in all the samples were determined and bloods were analysed using the polymerase chain reaction (PCR) for PCV2 nucleic acid. The pigs were monitored for clinical disease for up to 16 weeks. All the pigs that died or showed clinical signs of PMWS were necropsied and tissues examined by immunohistochemistry (IHC) for PCV2 antigen. When the tissues had histological lesions and a strong association with PCV2 antigen, the animal was deemed to have had PMWS. These results were correlated with the PCV2 serum antibody levels and PCV2 nucleic acid content in the blood of the individual pigs in the first week of life. The results indicate that there was no direct correlation between the levels of colostrum-derived PCV2 antibodies and the development of PMWS. However, they suggest that high levels of passively derived antibodies to PCV2 may delay the onset of PMWS.

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