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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
 
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
 
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
 
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Thursday, December 01, 2005: Viral Immunology, Volume 18, N°2, 333-341
Correlation between type of adaptive immune response against porcine circovirus type 2 and level of virus replication.
MEERTS P, VAN GUCHT S, COX E, VANDEBOSCH A, NAUWYNCK HJ
The aim of this study was to determine which immunological mechanisms lead to the replication of porcine circovirus type 2 (PCV2) in pigs. Sixteen gnotobiotic piglets were inoculated with PCV2 when they were 19-day old. Cyclosporin A (CysA) was then administered to some of those pigs in order to suppress the adaptive immunity and thus to make it possible to assess its effect on the development of PCV2 infection. Several analysis were carried out (lymphoid tissues biopsies, monitoring of clinical signs, identification of PCV2-specific antibodies by use of an immunoperoxydase monolayer assay - IPMA, detection of IFN-? mRNA by use of real-time reverse transcriptase polymerase chain reaction - RT-PCR, statistical analysis). The results showed that the adaptive immunity could be responsible for the differences observed in PCV2 replication in pigs.

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