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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Wednesday, February 10, 2010: Journal General Virol. 2010 Feb 10. [Epub ahead of print]
Colostral Transmission of Porcine Circovirus 2 (PCV2): Reproduction of PMWS in Pigs Feeding Milk from PCV2-Infected Sow and Postnatal Porcine Parvovirus Infection or immunostimulation.
Yooncheol Ha, Jeoung Hwa Shin and Chanhee Chae
Postweaning multisystemic wasting syndrome (PMWS) was reproduced in pigs fed colostrum and milk from porcine circovirus 2 (PCV2)-infected sows and postnatally infected with porcine parvovirus (PPV) or immunostimulated. Pregnant sows were intranasally inoculated with either PCV2 (n=5) or PCV2-free PK-15 cell lysates (control, n=10) 3 weeks before the expected farrowing date. Newborn piglets from five of the control sows were introduced to PCV2-infected sows (n=6 each sow) and allowed to feed on the colostrum for 12 hours and then 30 mL milk five times per day for 7 days. Newborn piglets from the other five control sows were fed colostrum and milk from their own sows. After 7 days, two piglets from each group were randomly selected to confirm PCV2 infection. Twenty-one pigs fed by PCV2-infected sows were randomly divided into three groups: 1, postnatal PPV infection; 2, immunostimulation; and 3, no postnatal treatment. Twenty-one pigs fed by uninfected sows were also randomly divided: 4, postnatal PCV2 and PPV infection; 5, postnatal PCV2 infection; and 6, negative control. Body weight was significantly greater in group 6 than groups 1, 2, and 4 at 49, 52, 56, 59, and 63 days of age. The typical granulomatous inflammatory reaction and lymphoid depletion of PMWS was observed in the lymph nodes of groups 1, 2, and 4 at 63 days of age. Group 3 had significantly fewer PCV2-positive cells than groups 1, 2, and 4. PCV2 shed from colostrum and milk is infectious and reproduces PMWS with postnatal PPV infection or immune stimulation.

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Saturday 11th February

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