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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Tuesday, November 01, 2005: Pig Journal Volume: 56 -
Post-weaning Multisystemic Wasting Syndrome (PMWS) in Farms: Defining disease and the role of Porcine Circovirus 2 (PCV2)
M. Turner, C. Schnier, K. Woodbine, L. Green, G. Medley and J. Slevin
The cause of PMWS is as yet undetermined. There has been great controversy over the role of PCV2 in the disease. Current case definitions for the disease vary, but all include the presence of PCV2 antigen or nucleic acid. In a cross-sectional study of 116 farms, there was little difference in the PCV2 serological profiles of PMWS positive, negative and recovered farms. However, PCV2 antigen levels were more raised in sick pigs on all farms. There were also high levels on farms where the farmers had not reported PMWS and some positive farms where no antigen was detected. Antigen levels were correlated with current mortality with PMWS on the farms. Porcine circovirus 2 was not included in the proposed case definition due to the uncertainty of its role in the disease.
There were 28 significant differences between the post-mortem examination (PME) of sick and healthy pigs, ignoring farm of origin. These differences were mainly enteric and respiratory. There were three significant differences between the histology results from sick and healthy pigs. These differences were significant in the ileoceacocolic lymph node. A case definition has been proposed using these significantly different signs.

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