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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Tuesday, November 01, 2005: Pig Journal Volume: 56 -
The use of PRACETAM (Paracetamol) premix in Post-weaning Multisystemic Wasting Syndrome (PMWS) and Post-weaning diets
L. Glattleider and N. Capdevielle
Controlled clinical trials were performed to evaluate the effect of PRACETAM in either PMWS or in a post-weaning diet.
The efficacy of PRACETAM was demonstrated by a controlled clinical trial under blind conditions in a pig herd chronically infected with PMWS. The therapeutic dose in the treated group was 30 milligrams of Paracetamol per kilograms body weight (1000 milligrams per kilogram of feed) for ten consecutive days and no concomitant antibiotic treatment was used. During the first period of the trial (between day 0 and day fourteen), only a small number of pigs died or lost weight. The difference between the treated and control group was not significant. During the second period of the trial, a statistically significant difference in the number of dead or wasting pigs was observed between the treated and control group and treatment with PRACETAM was concluded to have helped in reducing the mortality rate and the number of wasting piglets.
A controlled trial was carried out to evaluate the effect of PRACETAM on growth rate during the post-weaning period. Three hundred and fifty-one piglets were involved in this study, from the day of weaning (day zero) to the end of the post- weaning period (day 35), randomly divided into a control and a treated group and reared under different conditions. Under favourable conditions (5 piglets per box and completely slatted floor), a significant effect of PRACETAM was observed on growth performance with daily weight gain 55g higher than in the control group). Under unfavourable conditions (10 piglets per box, partially slatted floor and stimulation of the immune system by vaccination against Mycoplasma), an even greater effect of PRACETAM was seen throughout the growth period, despite the immune stimulation.

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