PMWS & PCVD
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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS National Pork Board PMWS Fact Sheet About PDNS (Jake Waddilive) CEI Emerging Disease Notices: PMWS / PDNS Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS. This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact. Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs. Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.
PMWS Research ArchivesPublished Tuesday, January 11, 2011: Transboundary and Emerging Diseases Jan 2011Prolonged Detection of PCV2 and Anti-PCV2 Antibody in Oral Fluids Following Experimental Inoculation J. R. Prickett, J. Johnson, M. P. Murtaugh, S. Puvanendiran, C. Wang, J. J. Zimmerman and T. Opriessnig The onset, level and duration of PCV2 and anti-PCV2 antibody in oral fluid were evaluated using samples collected from experimentally inoculated pigs for 98 days post-inoculation (DPI). Pigs (n = 24) were obtained at 3 weeks of age and randomly allocated to 4 treatment pens of 6 pigs each: (i) negative control group; (ii) inoculated with PCV2a (strain ISU 40895) on DPI 0; (iii) inoculated with PCV2a (strain ISU-40895) on DPI 0 and re-challenged at DPIs 35 and 70; (iv) inoculated with PCV2a (ISU-40895), PCV2b (PVG4072) and PCV2a (ISU-4838) on DPIs 0, 35 and 70, respectively. Serum was collected from each animal, and one oral fluid sample was collected from each pen (group) every other day from DPI 2 through DPI 14 and weekly through 98 DPI. Oral fluid samples were assayed for the presence of PCV2 by quantitative polymerase chain reaction (qPCR) and anti-PCV2 IgG, IgA and IgM antibody isotypes by enzyme-linked immunosorbant assay (ELISA). Serum was assayed for anti-PCV2 IgG by ELISA. Anti-PCV2 antibodies (IgG, IgM and IgA) were detected in oral fluid from experimentally inoculated pigs from DPI 14 with IgG and IgA clearly present at 98 DPI. PCV2 was detected in oral fluid samples from all pens of inoculated pigs at 2 DPI. Thereafter, PCV2 was detected in oral fluid throughout 98 DPI. Overall, the data indicated that PCV2 infection in swine is prolonged, persists in the face of an active antibody response and can be efficiently monitored using oral fluid specimens. To continue reading this article please click here Have you published information? To add please email the details |
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