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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
 
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
 
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
 
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Thursday, September 01, 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Impact of the route on the transfection effectiveness with infectious cloned genomic DNA of type 2 porcine circovirus.
GRASLAND B, BLANCHARD P, OGER A, BIGARRE L, CARIOLET R, JESTIN A
The transfection effectiveness of a cloned porcine circovirus type 2 (PCV2) inoculated by the natural transmission routes of the virus was investigated. Thirty-five specific-pathogen-free piglets (7 weeks old) were randomly divided into 4 groups. All piglets were inoculated with 400µg of PCV2 genomic DNA either intramuscularly - IM (Group 2), intratracheally - IT (Group 3) or oro-nasally - ON (Group 4). Group 1 was the control group. The experiment lasted 34 days following transfection. The seroconversion to PCV2 antibodies was determined by means of an ELISA test. A real time quantitative PCR was used to quantify the PCV2 genomes and an IPMA was used to quantify PCV2 infectious particles. The results showed that the PCV2 genomic DNA induced the development of PCV2 particles, but that the transfection was more efficient when the PCV2 genomic DNA was administered intramuscularly.


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