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Vaccination
Management
Disease Information
A PMWS update (Jake Waddilove)
ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
About PDNS (Jake Waddilive)
CEI Emerging Disease Notices: PMWS / PDNS
Conference and meetings archive
Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
 
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
 
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
 
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Thursday, September 01, 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Protection of piglets against a PCV2 experimental challenge by vaccinating gilts with an inactivated adjuvanted PCV2 vaccine.
CHARREYRE C, BESEME S, BRUN A, BUBLOT M, LAPOSTOLLE B , SIERRA P, VAGANAY A
The efficacy of an inactivated oil adjuvanted porcine circovirus type 2 (PCV2) vaccine (CIRCOVAC®) was studied. Twenty-two specific pathogen free gilts, seronegative for PCV2, were randomly divided into 2 groups. Gilts form Group 1 were vaccinated with CIRCOVAC® and the other group served as control. The vaccine was intramuscularly administered to the gilts 5 and 2 weeks before breeding and 2 weeks before farrowing. The same number of piglets born to either vaccinated gilts or control gilts were challenged intra-nasally with 6.3 log 10 CCID 50 of PCV2 at 3 and 4 weeks of age. Some piglets born to control gilts were not challenged and kept as control. The subsequent analyses caried out included monitoring of clinical signs, rectal temperature, weight and PCV2 ORF2 ELISA antibodies during 4 weeks, estimation of seric and rectal viral load by quantitative PCR (Q-PCR), PCV2 immunochemical detection in mesenteric lymph nodes after necrospy. The results showed that gilt vaccination with CIRCOVAC® was very efficient in protecting the piglets. It was also shown that in piglets born to vaccinated gilts and infected with PCV2, the clinical signs, lesions and replication of the virus were significantly reduced.


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Wednesday 8th October

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