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ABOUT PMWS & PDNS
National Pork Board PMWS Fact Sheet
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CEI Emerging Disease Notices: PMWS / PDNS
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Case Histories
Yorkshire Farm, UK - Mike Muirhead - Final Update, June 2002
Mike Muirhead's case history of a Yorkshire farm with PMWS and PDNS.
 
East Anglia Farm, UK - Philip Richardson
This paper charts the course and effects of the disease on a single herd as well as highlighting the economic impact.
Photographs
Clinical signs
Photos of the clinical signs that are seen generally in pigs with PMWS and PDNS. Includes skin lesions, enlarged lymph glands, wasting and dead pigs.
 
Post mortem (1)
Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS. Includes interstitial pneumonia, secondary bacterial infection, enlarged lymph nodes, oedema and intra cytoplasmic inclusions
 
Post mortem (2)
More Photos of the signs that are seen in post-mortem samples of pigs with PMWS and PDNS.


PMWS Research Archives

Published Thursday, September 01, 2005: Vet Microbiol - 30;110(1-2):141-6.
Genotyping of porcine circovirus type 2 from a variety of clinical conditions in China.
Wen L, Guo X, Yang H.
Genotypes of porcine circovirus type 2 (PCV2) in clinical tissue specimens collected from pigs of different region in China between 2001 and 2003 were analyzed by PCR and restriction fragment length polymorphism (RFLP) analysis of PCV2 genomic DNA encompassing the complete ORF2. The results showed that nine different genotypes (A-I) were identified and designated CHN-2A, CHN-2B, CHN-2C, CHN-2D, CHN-2E, CHN-2F, CHN-2G, CHN-2H and CHN-2I, respectively. Amongst the genotypes, 0.6% were CHN-2A (1/173), CHN-2B (1/173) and CHN-2C (1/173) RFLP profile; 2.3% were CHN-2F (4/173) and CHN-2G (4/173); 5.8% were CHN-2D (10/173); 8.6% were CHN-2E (15/173); 18.5% were CHN-2I (32/173) and 60.7% were CHN-2H (105/173). Therefore, our results suggest that CHN-2H is the dominant genotype of PCV2 prevailing in China. Sequence analysis revealed that ORF2 genes of different genotypic PCV2 exhibited the variation extent of 90.5-99.5% and 88-100% in nucleotide and amino acid respectively. The deduced amino acid sequences alignment of the capsid protein encoded by ORF2 of PCV2 presented that three major regions with greater heterogeneity existed at residues 57-90, 121-136 and 180-191 among nine genotypic PCV2. It was concluded that there exist variation in ORF2 genes of different genotypic PCV2 prevailing in China.

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