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PMWS Research Archives
Published Nov 2006: Vet Rec. 2006 Nov 25;159(22):737-42Survey of pigs' kidneys with lesions consistent with PMWS and PDNS and ochratoxicosis. Part 1: concentrations and prevalence of ochratoxin A.
Gresham A, Done S, Livesey C, Macdonald S, Chan D, Sayers R, Clark C, Kemp P.
One thousand condemned pigs' kidneys were collected in February 2002 from two pig abattoirs in England to assess the possible contribution of ochratoxicosis to postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome...
Published Nov 2006: Vet Pathol. 2006 Nov;43(6):993-7
Immunohistochemical MHC-II and interleukin 2-R (CD25) expression in lymph nodes of pigs with spontaneous postweaning multisystemic wasting syndrome (PMWS).
Mandrioli L, Sarli G, Zengarini M, Panarese S, Marcato PS.
Immunohistochemical expression of immunocompetent cells bearing major histocompatibility complex (MHC-II) and interleukin 2-R (IL2-R) (CD25) molecules was performed on lymph nodes with spontaneous postweaning multisystemic wasting syndrome (PMWS). Control...
Published Nov 2006: J Gen Virol. 2006 Nov;87(Pt 11):3215-23.
Porcine circovirus type 2 replicase binds the capsid protein and an intermediate filament-like protein.
Timmusk S, Fossum C, Berg M.
Porcine circovirus type 2 (PCV2) is an important porcine pathogen that establishes persistent subclinical infections but may, on activation, contribute to the development of post-weaning multisystemic wasting syndrome (PMWS). This disease is characterized...
Published Oct 2006: Research in Veterinary Science - Available online 24 October 2006
Sow porcine circovirus type 2 (PCV2) status effect on litter mortality in postweaning multisystemic wasting syndrome (PMWS)
M. Calsamiglia, L. Fraile, A. Espinal, A. Cuxart, C. Seminati, M. Martína,, E. Mateua,, M. Domingo and J. Segalés
Previous studies have described a “litter effect” associated with mortality in postweaning multisystemic wasting syndrome (PMWS) affected farms. The main objective of this study was to evaluate litter mortality in different PMWS affected farms and to...
Published Oct 2006: Immunology. 2006 Oct 13; [Epub ahead of print]
Silencing of natural interferon producing cell activation by porcine circovirus type 2 DNA.
Vincent IE, Balmelli C, Meehan B, Allan G, Summerfield A, McCullough KC.
Porcine circovirus type 2 (PCV2) infection of natural interferon producing cells (NIPCs) impairs the induction of interferon (IFN)-alpha and tumour necrosis factor (TNF)-alpha by cytosine-phosphorothioate-guanine (CpG) oligodeoxynucleotides (ODNs), thereby...
Published Oct 2006: Research in Veterinary Science Volume 81, Issue 2, Pages 287-292
PCR detection of porcine circovirus type 2 (PCV2) DNA in blood, tonsillar and faecal swabs from experimentally infected pigs
A. Caprioli, F. McNeilly, I. McNair, P. Lagan-Tregaskis, J. Ellis, S. Krakowka, J. McKillen, F. Ostanello and G. Allan
PCV2 infection is now recognized as the major factor in the development of post-weaning multisystemic wasting syndrome (PMWS). In this study we evaluated the use of PCR to detect the presence of PCV2 DNA in blood, faecal and tonsillar swabs collected...
Published Oct 2006: J. Gen. Virol., 87: 2923 - 2932
Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence
T. Opriessnig, N. E. McKeown, E.-M. Zhou, X.-J. Meng and P. G. Halbur
There are marked differences in the clinical expression of diseases associated with porcine circovirus type 2 (PCV2) in the field. The objective of this study was to compare the sequences and pathogenicity of PCV2 isolates from field cases with and without...
Published Oct 2006: Can J Vet Res. 2006 Oct;70(4):269-76
The role of immunostimulation in the development of postweaning multisystemic wasting syndrome in pigs under field conditions.
Haruna J, Hanna P, Hurnik D, Ikede B, Miller L, Yason C.
We evaluated the effects of immunostimulation in the development of postweaning multisystemic wasting syndrome (PMWS) in 930 pigs 53 to 54 d old in a grower/finisher barn with a history of PMWS. The pigs were allocated to 5 treatment groups: 4 groups...
Published Sep 2006: Virology Article in Press, Corrected Proof -
Molecular evolution of porcine circovirus type 2 genomes: Phylogeny and clonality
A. Olvera, M. Cortey and J. Segalés
Porcine circoviruses (PCVs) type 1 (PCV1) and type 2 (PCV2) show high levels of nucleotide similarity, but PCV1 is considered non-pathogenic and PCV2 has been associated with several disease outcomes in pigs, mainly postweaning multisystemic wasting syndrome...
Published Sep 2006: Vet Pathol. 43(5):718-25
Potentiation of Porcine Circovirus 2-induced Postweaning Multisystemic Wasting Syndrome by Porcine Parvovirus Is Associated with Excessive Production of Tumor Necrosis Factor-{alpha}.
Kim J, Ha Y, Chae C.
This study investigated the potentiation of porcine circovirus 2 (PCV2)-induced postweaning multisystemic wasting syndrome by porcine parvovirus (PPV) and found it was associated with excessive production of tumor necrosis factor-alpha (TNF-alpha). Colostrum-deprived...
Published Sep 2006: Virology. [Epub ahead of print]
Molecular evolution of porcine circovirus type 2 genomes: Phylogeny and clonality.
Olvera A, Cortey M, Segales J.
Porcine circoviruses (PCVs) type 1 (PCV1) and type 2 (PCV2) show high levels of nucleotide similarity, but PCV1 is considered non-pathogenic and PCV2 has been associated with several disease outcomes in pigs, mainly postweaning multisystemic wasting syndrome...
Published Sep 2006: Rev Argent Microbiol. 2006 Jul-Sep;38(3):130-3
Detection of Mycoplasma suis in clinical cases with postweaning multisystemic wasting syndrome in swine
Pereyra NB, Sarradell JE, Cane FD, Francois SE, Pidone CL, Comba ER, Rodriguez F, Guglielmone AA.
Mycoplasma suis is a swine erythrocyte obligatory parasite. Its presence may result in chronic or acute anaemia in different pig categories. It is considered that the postweaning multisystemic wasting syndrome (PMWS) is caused by porcine circovirus...
Published Aug 2006: Veterinary Microbiology Volume 116, Issues 1-3 , 25 August 2006, Pages 60-68
Infection of pigs in Ireland with lymphotropic γ-herpesviruses and relationship to postweaning multisystemic wasting syndrome
Kenneth J. McMahon, Donal Minihan, Eva M. Campion, Sinéad T. Loughran, Gordon Allan, Francis McNeilly and Dermot Walls
Three species of porcine lymphotropic herpesviruses (PLHVs) have been described but there are few reports on the distribution and prevalence of these viruses in domestic pigs. We aimed to determine the PLHV status of Irish commercial pig herds, and to...
Published Aug 2006: Viral Immunol.19(2):189-95 Abstract)
Cytokine and C-reactive protein profiles induced by porcine circovirus type 2 experimental infection in 3-week-old piglets.
Stevenson LS, McCullough K, Vincent I, Gilpin DF, Summerfield A, Nielsen J, McNeilly F, Adair BM, Allan GM.
The purpose of this study was to determine serum profiles of cytokines at a protein level and Creactive protein (CRP) during the development of postweaning multisystemic wasting syndrome (PMWS) in experimentally inoculated pigs. Levels of serum IFN-alpha,...
Published Aug 2006: Livestock Science Volume 103, Issues 1-2, Pages 104-115
The welfare of finishing pigs in two contrasting housing systems: Fully-slatted versus straw-bedded accommodation
K. Scott, D.J. Chennells, F.M. Campbell, B. Hunt, D. Armstrong, L. Taylor, B.P. Gill and S.A. Edwards
Four consecutive studies were carried out over a 3-year period to assess the health and welfare implications of housing finishing pigs in either fully-slatted or straw-bedded accommodation. In each study, 1024 (Large White × Landrace) × Large White pigs,...
