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PMWS Research Archives
Published Dec 2011: Veterinary Microbiology Volume 154, Issues 1-2, 29 December 2011, Pages 104-112Porcine Circovirus Type 2 Potentiates Morbidity of Salmonella enterica serovar Choleraesuis in Cesarean-Derived, Colostrum-Deprived Pigs
A. Takada-Iwao, M. Nakanishi, J. Souma, S. Chikata, Y. Okuda, Y. Imai and S. Sato
Problem addressed Porcine circovirus type 2 (PCV2) and Salmonella enterica subspecies enterica serovar Choleraesuis (S. Choleraesuis) are two leading causes of economic loss in the swine industry. Although S. Choleraesuis...
Published Dec 2011: Veterinary Microbiology Volume 154, Issues 1-2, 29 December 2011, Pages 185-190
Leukogram Abnormalities in Gnotobiotic Pigs Infected with Porcine Circovirus Type 2
P.C. Gaugera, K.M. Lagera, A.L. Vincent, T. Opriessnig, A.K. Cheung, J.E. Butler and M.E. Kehrli Jr
Porcine circovirus type 2 (PCV2) is a single-stranded circular DNA virus that is the causative agent of porcine circovirus associated disease (PCVAD), a disease complex affecting swine around the world. Although this virus is believed to negatively affect...
Published Dec 2011: Veterinary Microbiology Volume 153, Issues 3-4, 15 December 2011, Pages 229-239
Postweaning Multisystemic Wasting Syndrome Produced in Gnotobiotic Pigs Following Exposure to Various Amounts of Porcine Circovirus Type 2a or Type 2b
P.C. Gauger, K.M. Lager, A.L. Vincent, T. Opriessnig, M.E. Kehrli Jr and A.K. Cheung
In late 2005, a postweaning, high mortality syndrome spread rapidly through finishing barns in swine dense areas of the United States. Diagnostic investigations consistently detected porcine circovirus type 2 (PCV2) from diseased tissues. Subsequent genetic...
Published Dec 2011: Veterinary Microbiology Volume 153, Issues 3-4, 15 December 2011, Pages 377-381
Torque Teno Sus Virus 1 and 2 Viral Loads in Postweaning Multisystemic Wasting Syndrome (PMWS) and Porcine Dermatitis and Nephropathy Syndrome (PDNS) Affected Pigs
M. Aramouni, J. Segalés, M. Sibila, G.E. Martin-Valls, D. Nieto and T. Kekarainen
Torque teno viruses (TTV) are small, non-enveloped viruses with a circular single-stranded DNA genome, which are considered non-pathogenic. However, TTVs have been eventually linked to human diseases. TTVs infecting pigs, Torque teno sus virus 1 (TTSuV1)...
Published Dec 2011: Virology Journal 2011, 8:543
Prevalence of Porcine Circovirus-like Agent P1 in Jiangsu, China
Libin Wen, Kongwang He, Hanchun Yang, Zhengyu Yu, Aihua Mao, Shulin Zhong, Yanxiu Ni, Xuehan Zhang, Bin Li, Xiaomin Wang, Junming Zhou, Rongli Guo, Lixin Lv and Jieyuan Jiang
Recently, we identified a novel porcine circovirus type 2-like agent P1 isolate from swine. The present study represents the first survey of P1 prevalence in swine herds from Jiangsu, China, by using PCR targeting the complete genome of P1. Prevalences...
Published Dec 2011: Virus Res. 2011 Dec 9. [Epub ahead of print]
Immunology of Porcine Circovirus Type 2 (PCV2).
Darwich L, Mateu E.
The emergence of porcine circovirus type 2 (PCV2) associated diseases and particularly postweaning multisystemic wasting syndrome (PMWS) was a shock for the swine industry and formulated a considerable challenge for researchers in the area of viral immunology...
Published Dec 2011: Virus Genes, Volume 43, Number 3, December 2011 , pp. 376-379(4)
Genetic Detection and Analysis of Porcine Bocavirus Type 1 (PoBoV1) in European Wild Boar (Sus scrofa)
Cadar, Dániel; Cságola, Attila; Lorincz, Márta; Tombácz, Kata; Kiss, Timea; Spînu, Marina; Tuboly, Tamás
Novel porcine parvoviruses showing the genetic characteristics of bocaviruses have recently been identified. The first such porcine bocavirus (PoBoV1), described as boca-like virus (PBo-likeV), was discovered in PMWS affected pigs in Sweden. Later, several...
Published Dec 2011: Acta Vet Hung. 2011 Dec;59(4):511-20.
Profiles of Seroconversion to Porcine Circovirus Type 2 in Herds Affected and not Affected by Postweaning Multisystemic Wasting Syndrome.
Podgórska K, Stadejek T.
The aim of the present study was to explore the usefulness of serological methods in the diagnosis of postweaning multisystemic wasting syndrome (PMWS). The study was carried out in 4 PMWS-affected and 6 control farms. Based on the serological profiles,...
Published Dec 2011: Acta Virol. 2011;55(3):267-71.
Prevalence of Porcine Crcovirus 2 Infection in Pig Population in Slovakia.
Csank T, Pistl J, Polláková J, Holoda E, Harvan M.
The prevalence of porcine circovirus 2 (PCV-2) infection in the pig population in Slovakia was investigated. Sera from pigs suspected for post-weaning multisystemic wasting syndrome (PMWS) as well as clinically healthy pigs were tested for viral DNA and...
Published Dec 2011: Vet Microbiol. 2011 Dec 2. [Epub ahead of print]
Lack of Effect of Piglet Vaccination Against Porcine Circovirus Type 2 (PCV2) on Serum Viral Loads of Torque Teno Sus Virus 2 (TTSuV2).
Nieto D, Aramouni M, Sibila M, Fraile L, Kekarainen T, Segalés J.
Anelloviruses are small, non-enveloped viruses with circular single stranded DNA, which infect a number of animal species as well as humans. In pigs, two distinct Torque teno sus virus (TTSuV) species have been described so far, being one of them linked...
Published Dec 2011: Veterinary Research 2011, 42:115
Porcine Circovirus Type 2 (PCV2) Infection Decreases the Efficacy of an Attenuated Classical Swine Fever Virus (CSFV) Vaccine
Yu-Liang Huang, Victor Fei Pang, Chun-Ming Lin, Yi-Chieh Tsai, Mi-Yuan Chia, Ming-Chung Deng, Chia-Yi Chang and Chian-Ren Jeng
The Lapinized Philippines Coronel (LPC) vaccine, an attenuated strain of classical swine fever virus (CSFV), is an important tool for the prevention and control of CSFV infection and is widely and routinely used in most CSF endemic areas, including Taiwan....
Published Nov 2011: Journal of Virological Methods - In Press, Uncorrected Proof
A Multiple SYBR Green I-Based Real-Time PCR System for the Simultaneous Detection of Porcine Circovirus Type 2, Porcine Parvovirus, Pseudorabies Virus and Torque Teno Sus Virus 1 and 2 in Pigs
Lester J. Pérez, Carmen L. Perera, Maria T. FrÃas, José I.Núñez, LliliannE Ganges, Heidy DÃaz de Arce
Multiple viral infections are common in pigs under intensive production conditions. All five of the viruses included in this study are associated with multifactorial diseases that cause significant economic losses in swine farming worldwide. The development...
Published Nov 2011: Virology Journal 2011, 8:517
Co-Existence of Multiple Strains of Porcine Circovirus Type 2 in the same Pig from China
Shao-Lun Zhai, Sheng-Nan Chen, Zu-Zhang Wei, Jian-Wu Zhang, Lv Huang, Tao Lin, Cheng Yue, Duo-Liang Ran, Shi-Shan Yuan, Wen-Kang Wei and Jin-Xue Long
Pigs are often co-infected by different viral strains from the same virus. Up to now, there are few reports about co-existence of different porcine circovirus type 2 (PCV2) strains in China. The aim of this study was to evaluate it in Chinese swine herds....
Published Nov 2011: Virus Res. 2011 Nov 9. [Epub ahead of print]
A Nine-Base Nucleotide Sequence in the Porcine Circovirus Type 2 (PCV2) Nucleocapsid Gene Determines Viral Replication and Virulence.
Krakowka S, Allan G, Ellis J, Hamberg A, Charreyre C, Kaufmann E, Brooks C, Meehan B.
Porcine circovirus type 2 (PCV2) was retrospectively identified by serology in swine populations as an asymptomatic infection at least 25 years prior to the first reported case of PCV2-associated postweaning multisystemic wasting syndrome (PMWS). To investigate...
Published Nov 2011: Journal of Virological Methods - In Press, Uncorrected Proof
Use of PCR-Based Assays for the Detection of the Adventitious Agent Porcine Circovirus Type 1 (PCV1) in Vaccines, and for Confirming the Identity of Cell Substrates and Viruses used in Vaccine Production
Deepak Kumar, Nathan M. Beach, Xiang-Jin Meng, Nagendra R. Hegde
Safety and quality are important issues for vaccines. Whereas reversion to virulence poses a safety risk with live attenuated vaccines, the potential for the presence of adventitious agents is also an issue of vaccine quality. The recent detection or...
