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PMWS & PCVD

PMWS Research Archives

Published Oct 2012: Research in Veterinary Science, Volume 93, Issue 2, October 2012, Pages 1039-1041
Comparison of Torque Teno Sus Virus (TTSuV) Viral Load in Porcine Circovirus Type 2 Vaccinated and Non-vaccinated Pig Herds
Sungseok Lee, Jeongyeon Shin, Chiyong Kim, Young S. Lyoo
Torque Teno Sus Virus (TTSuV) viral load in accordance with the Porcine Circovirus Type 2 (PCV2) infection and age of two pig herds was determined. A total of 100 and 155 piglets from two farms were divided into two groups. Half of the piglets from each...

Published Oct 2012: J. Virol. October 2012 ; 86:10895; doi:10.1128/JVI.01817-12
Complete Genome Sequence of a Novel Field Strain of Rearranged Porcine Circovirus Type 2 in Southern China
Zhen Huang, Shuo Su, Chun-ya Wei, Jie-xiong Xie, Wan-jun Zhu, Ji-dang Chen, Heng Wang and Guihong Zhang
We report here the complete genomic sequence of a novel porcine circovirus type 2 (PCV2) strain, which is supposed to be the result of natural genetic recombination between the ORF1 gene of genotype PCV2b-1B and the ORF2 gene of PCV2b-1C. Further analyses...

Published Sep 2012: J. Virol. September 2012 ; 86:9536; doi:10.1128/JVI.01406-12
Complete Genome Sequence of Porcine Circovirus 2b Strain CC1
Xin Yang, Fuwang Chen, Yuhang Cao, Daxing Pang, Hongsheng Ouyang and Linzhu Ren
A porcine circovirus 2 (PCV2) strain, designated CC1, was isolated and purified from tissue samples from pigs with wasting syndromes in China. We report the complete genome sequence of PCV2b strain CC1 with a deletion of C at position 1053 resulting in...

Published Aug 2012: J. Virol. August 2012 ; 86:8911; doi:10.1128/JVI.01377-12
In Vitro Intragenomic Rearrangement of Porcine Circovirus Type 2
Libin Wen, Kongwang He, Yanxiu Ni, Xuehan Zhang, Bin Li, Xiaomin Wang, Rong li Guo, Zhengyu Yu, Aihua Mao, Junming Zhou, Lixin Lv and Jieyuan Jiang
We report here for the first time the genome sequence of a rearranged porcine circovirus type 2 (PCV2) strain, CH-IVT1, isolated from PCV2-infected PK-15 cells. The complete circular genome of the CH-IVT1 is 605 nucleotides (nt) in length. The finding...

Published Aug 2012: PLoS One. 2012; 7(8): e41565 Published online 2012 August 24.
A Novel Porcine Circovirus-Like Agent P1 Is Associated with Wasting Syndromes in Pigs
Libin Wen, Kongwang He,* Qi Xiao, Zhengyu Yu, Aihua Mao, Yanxiu Ni, Xuehan Zhang, Bin Li, Xiaomin Wang, Rongli Guo, Junming Zhou, Lixin LV, and Jieyuan Jiang
A novel porcine pathogen tentatively named P1, which was obtained from the sera of the pigs exhibiting clinical signs of postweaning multisystemic wasting syndrome (PMWS) experimentally caused the classical clinic signs and pathologic lesions of the disease...

Published Aug 2012: J. Virol. August 2012 ; 86:8911; doi:10.1128/JVI.01377-12
In Vitro Intragenomic Rearrangement of Porcine Circovirus Type 2
Libin Wen, Kongwang He, Yanxiu Ni, Xuehan Zhang, Bin Li, Xiaomin Wang, Rong li Guo, Zhengyu Yu, Aihua Mao, Junming Zhou, Lixin Lv and Jieyuan Jiang
We report here for the first time the genome sequence of a rearranged porcine circovirus type 2 (PCV2) strain, CH-IVT1, isolated from PCV2-infected PK-15 cells. The complete circular genome of the CH-IVT1 is 605 nucleotides (nt) in length. The finding...

Published Aug 2012: Infection, Genetics and Evolution, Volume 12, Issue 6, August 2012, Pages 1163-1171
Phylogeny and Evolutionary Genetics of Porcine Parvovirus in Wild Boars
Dániel Cadar, Ádám Dán, Kata Tombácz, Márta Lőrincz, Timea Kiss, Zsolt Becskei, Marina Spînu, Tamás Tuboly, Attila Cságola
Porcine parvovirus (PPV) is widespread among swine and is responsible for reproductive failure of susceptible sows, characterized by embryonic and fetal death. Studies showed that PPV in domestic pig is genetically diverse and some strains differ from...

Published Aug 2012: Research in Veterinary Science - Volume 93, Issue 1, August 2012, Pages 538–543
Detection of Circoviruses and Porcine Adenoviruses in Water Samples Collected from Swine Manure Treatment Systems
A. Viancelli, L.A.T. Garcia, A. Kunzb, R. Steinmetz, P.A. Esteves, C.R.M. Barardi
Samples collected from two swine manure treatment systems including: swine manure treatment system and demonstrative unit (SMTS and DU), were analyzed by qPCR to quantify the amount of porcine adenovirus (PAdV) and porcine circovirus (PCV2) present. Positive...

Published Aug 2012: Journal of Comparative Pathology,Volume 147, Issues 2–3, August–October 2012, Pages 285–295
Simultaneous Porcine Circovirus Type 2 and Mycoplasma hyopneumoniae Co-inoculation does not Potentiate Disease in Conventional Pigs
M. Sibila, M. Fort, M. Nofrarías, A. Pérez de Rozas, I. Galindo-Cardiel, E. Mateu, J. Segalés
The aim of this study was to assess the effect of simultaneous experimental inoculation of porcine circovirus type 2 (PCV2; intranasal delivery) and Mycoplasma hyopneumoniae (Mhyo; transtracheal delivery) into conventional, seropositive 6-week-old piglets....

Published Aug 2012: Free Radical Biology and Medicine, Volume 53, Issue 3, 1 August 2012, Pages 395-405
Selenium Blocks Porcine Circovirus Type 2 Replication Promotion Induced by Oxidative Stress by Improving GPx1 Expression
Xingxiang Chen, Fei Ren, John Hesketh, Xiuli Shi, Junxian Li, Fang Gan, Kehe Huang
Porcine circovirus type 2 (PCV2) is recognized as a key infectious agent in postweaning multisystemic wasting syndrome (PMWS), but not all pigs infected with PCV2 will develop PMWS. The aim of this work was to explore the relationships among PCV2 infection,...

Published Jul 2012: Vet J. 2012 Jul 27. [Epub ahead of print]
Commercial Porcine Circovirus Type 2 Vaccines: Efficacy and Clinical Application.
Chae C.
Porcine circovirus type 2 (PCV2) is the one of the most economically important pathogens of pigs. After postweaning multisystemic wasting syndrome (PMWS) was first identified and reported in western Canada in 1991, it took 13years for the first commercial...

Published Jul 2012: The Veterinary Journal, In Press, Corrected Proof, Available online 19 July 2012
Subclinical Porcine Circovirus Infection: What Lies Beneath
Dominiek Maes
...

Published Jul 2012: PLoS One. 2012; 7(7): e41463. Published online 2012 July 19.
A Porcine Circovirus Type 2 (PCV2) Mutant with 234 Amino Acids in Capsid Protein Showed More Virulence In Vivo, Compared with Classical PCV2a/b Strain
Longjun Guo, Yujie Fu, Yiping Wang, Yuehua Lu, Yanwu Wei, Qinghai Tang, Peihu Fan, Jianbo Liu, Long Zhang, Feiyan Zhang, Liping Huang, Dan Liu, Shengbin Li, Hongli Wu, and Changming Liu*
Background Porcine circovirus type 2 (PCV2) is considered to be the primary causative agent of postweaning multisystemic wasting syndrome (PMWS), which has become a serious economic problem for the swine industry worldwide. The major genotypes, PCV2a...

Published Jul 2012: The Veterinary Journal, In Press, Corrected Proof, Available online 17 July 2012
C-Terminal Heat Shock Protein 70 of Mycobacterium tuberculosis as a Molecular Adjuvant for DNA Vaccination with the Porcine Circovirus Type 2 ORF2 (Capsid) Gene in Mice
Fang Fu, Huabin Tian, Xuesong Li, Yuekun Lang, Guangzhi Tong, Siguo Liu, Haizhong Li, Wei Wang, Xi Li, Xin Chen
Mycobacterium tuberculosis heat shock protein 70 (HSP70) and the peptide binding C-terminal portion of HSP70 (amino acids 359-610; HSP70c) exert an adjuvant effect when used in vaccines. To enhance the immunogenicity of a DNA vaccine against porcine circovirus...

Published Jul 2012: Veterinary Microbiology Volume 157, Issues 3–4, 15 June 2012, Pages 294–303
Oral Vaccination with Attenuated Salmonella enterica Serovar Typhimurium Expressing Cap protein of PCV2 and its Immunogenicity in Mouse and Swine Models
Xin-Gang Xu, Hong-Ni Zhao, Qi Zhang, Li Ding, Zhao-Cai Li, Wei Li, Hung-Yi Wu, Kuo Pin Chuang, De-Wen Tong, Hung-Jen Liu
Attenuated Salmonella enterica serovar Typhimurium (S. typhimurium) was selected as a transgenic vehicle for the development of oral vaccines against Porcine circovirus type 2 (PCV2). The Cap-encoding gene of PCV2 was amplified by PCR and cloned into...

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