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PMWS Research Archives
Published Sep 2009: Journal of Virological Methods, Volume 160, Issues 1-2, September 2009, Pages 210-214Multiplex PCR and Multiplex RT-PCR for Inclusive Detection of Major Swine DNA and RNA Viruses in Pigs with Multiple Infections
Hirohito Ogawa, Osamu Taira, Takuya Hirai, Hiromi Takeuchi, Aki Nagao, Yoshiki Ishikawa, Kotaro Tuchiya, Tetsuo Nunoya, Susumu Ueda
Multiplex PCR and multiplex RT-PCR were developed to identify nine viruses in pigs with multiple infections. These viruses are: porcine circovirus type 2 (PCV2), suid herpesvirus 1, porcine parvovirus (PPV), porcine reproductive and respiratory syndrome...
Published Aug 2009: Preventive Veterinary Medicine - Volume 90, Issues 3-4, 1 August 2009, Pages 168-179
Individual Risk Factors for Post-weaning Multisystemic Wasting Syndrome (PMWS) in Pigs: A Hierarchical Bayesian Survival Analysis
N. Rose, E. Evenoa, B Graslanda, A.Nignol, A. Oger, A. Jestin and F. Madec
Risk factors for Post-weaning Multisystemic Wasting Syndrome (PMWS) at the pig level were identified using data from a longitudinal study in seven PMWS-affected farms in France. In each farm, a representative sample of 120 pigs (180 in one farm) was randomly...
Published Aug 2009: Research in Veterinary Science - Volume 87, Issue 1, August 2009, Pages 157-160
Detection of Porcine Circovirus Type 2 (PCV2) Variants PCV2-1 and PCV2-2 in Brazilian Pig Population
Ciacci-Zanella JR, Simon NL, Pinto LS, Viancelli A, Fernandes LT, Hayashi M, Dellagostin OA, Esteves PA.
In the present study whole genome of six Brazilian isolates of PCV2 were sequenced, analyzed and compared with 35 other sequences (24 from other countries and 17 from Brazil). The phylogenetic analysis showed that mostly Brazilian variants of PCV2 were...
Published Aug 2009: The Veterinary Record Aug 2009 165:143-146 (2009)
Prevalence of Postweaning Multisystemic Wasting Syndrome in Pigs Sired by 13 Hungarian Landrace Boars
I. Szabó, DrMedVet, PhD, A. Bartus, ScAgr, Z. Harsányi, ScAgr, G. Lukács, DrVetMed, T. Molnár, DrVetMed and L. Stipkovits, DrMedVet, PhD, DVSc
Between February 20 and October 31, 2003, 2034 sows were inseminated with semen collected from 13 Hungarian Landrace boars. Altogether 16,013 piglets were born: 13,801 (86·2 per cent) alive, 796 (4·97 per cent) stillborn and 156 (0·97 per cent) mummified....
Published Aug 2009: The Veterinary Record, Aug 2009; 165: 262 - 265.
Evaluation of the Safety of Four Porcine Circovirus Type 2 Tissue Homogenate Vaccines in a Pig Bioassay
R. B. Baker, DVM, MS, D. M. Madson, DVM, A. R. Patterson, DVM, MS and T. Opriessnig, DrMedVet, PhD
Ten four-week-old porcine circovirus type 2 (PCV-2) naive piglets were housed individually in a HEPA-filtered isolator and were randomly assigned to one of six treatment groups. Each of the two pigs in groups 1 to 4 received two intramuscular doses of...
Published Jul 2009: Veterinary Microbiology - Volume 138, Issues 1-2, 2 July 2009, Pages 53-61
Pig-major Acute Phase Protein and Haptoglobin Serum Concentrations Correlate with PCV2 Viremia and the Clinical Course of Postweaning Multisystemic Wasting Syndrome
L. Grau-Roma, P.M.H. Heegaard, C.K. Hjulsager, M. Sibila, C.S. Kristensen, A. Allepuz, M. Piñeiro, L.E. Larsen, J. Segalés, and L. Fraile
The aim of the present longitudinal study was to assess the evolution of two acute phase proteins (APPs), pig-major acute phase protein (pig-MAP) and haptoglobin (HPT), in serum from pigs that developed postweaning multisystemic wasting syndrome (PMWS)...
Published Jun 2009: Veterinary Microbiology - Available online 11 June 2009
Prevalence of Swine Torque Teno Virus Genogroups 1 and 2 in Japanese Swine with Suspected Post Weaning Multisystemic Wasting Syndrome and Porcine Respiratory Disease Complex
Osamu Tair, Hirohito Ogawa, Aki Nagaoa, Kotaro Tuchiya, Tetsuo Nunoya and Susumu Ueda
Torque teno virus (TTV) was first isolated from a human hepatitis patient in 1997. TTV was also identified in several animals, including pigs, cattle, sheep, cats and dogs. In this study, we analysed the prevalence of swine TTV genogroups 1 (TTV1) and...
Published Jun 2009: Veterinary Microbiology - Available online 11 June 2009.
Transmission of Different Variants of PCV2 and Viral Dynamics in a Research Facility with Pigs Mingled from PMWS-Affected Herds and Non-Affected Herds
K. Dupont,C.K. Hjulsager, C.S. Kristensen, P. Baekbo and L.E. Larsen
Postweaning Multisystemic Wasting Syndrome (PMWS) has been identified in most swine-producing countries worldwide. The disease has resulted in significant health challenges and economic damage to the swine industry. The aim of this study was to determine...
Published Jun 2009: Veterinary Microbiology - Available online 8 June 2009
Swine Torque Teno Virus (TTV) Infection and Excretion Dynamics in Conventional Pig Farms
M. Sibila, L. Martinez-Guinó, E. Huerta, A. Llorens, M. Mora, L. Grau-Roma, T. Kekarainen and J. Segalés
Torque teno virus (TTV) is a non-enveloped, single stranded DNA (ssDNA) virus infecting human and non-primate species. Two genogroups of TTV (TTV1 and TTV2) have been described in swine so far. In the present study, TTV1 and TTV2 prevalences in...
Published Jun 2009: Journal of Virology, June 2009, p. 6039-6047, Vol. 83, No. 12
JNK and p38 Mitogen-Activated Protein Kinase Pathways Contribute to Porcine Circovirus Type 2 Infection
Li Wei, Zhongwu Zhu, Jing Wang, and Jue Liu
Infection with a wide variety of viruses often perturbs host cell signaling pathways including the Jun NH2-terminal kinase/stress-activated kinase (JNK/SAPK) and the p38 mitogen-activated protein kinase (p38/MAPK), which are important components of cellular...
Published May 2009: Res Vet Sci. 2009 May 19. [Epub ahead of print]
Distribution of Antibodies Against Porcine Circovirus Type-2 (PCV2) in Single Site and Multi-Site Farrow-to-Finish Farms in Brazil.
Gerber PF, Galinari GC, Silva MX, Campos FS, Reis AC, Lobato ZI.
A comparative serologic study was performed in seven single site (SS) farrow-to-finish farms and four multi-site (MS) farrow-to-finish farms, with or without post-weaning multisystemic wasting syndrome (PMWS). In each farm, 30 blood samples were collected...
Published May 2009: Virology. 2009 Jun 20;389(1-2):91-9. Epub May 6 2009
Porcine Reproductive and Respiratory Syndrome Virus as a Vector: Immunogenicity of Green Fluorescent Protein and Porcine Circovirus Type 2 Capsid Expressed from Dedicated Subgenomic RNAs.
Pei Y, Hodgins DC, Wu J, Welch SK, Calvert JG, Li G, Du Y, Song C, Yoo D.
Porcine reproductive and respiratory syndrome virus (PRRSV) is the causative agent of PRRS, which is characterized by late-term abortions in sows and respiratory disease in young pigs. Using an infectious cDNA clone of North American PRRSV strain P129,...
Published May 2009: The Veterinary Record, May 2009; 164: 599 - 600.
Efficacy of Different Disinfectants In Vitro Against Porcine Circovirus Type 2.
H. B. Kim, K. S. Lyoo, and H. S. Joo
No abstract is available for this article. See 'Journal...
Published Apr 2009: The Veterinary Record, Apr 2009; 164: 519 - 523.
Application of a Protocol for the Diagnosis of Postweaning Multisystemic Wasting Syndrome in Italy
G. Sarli, F. Ostanello, F. Morandi, L. Fusaro, M. Gnudi, B. Bacci, A. Nigrelli, L. Alborali, M. Dottori, F. Vezzoli, G. Barigazzi, L. Fiorentini, V. Sala, G. Leotti, and F. Joisel
Samples of superficial inguinal and bronchial lymph nodes, ileum, tonsil and lung were taken from three to five pigs on each of 61 farms with a clinical history of postweaning multisystemic wasting syndrome (PMWS). The samples were examined histologically...
Published Apr 2009: Veterinary Microbiology - Available online 19 April 2009
Bordetella bronchiseptica aroA Mutant as a Live Vaccine Vehicle for Heterologous Porcine Circovirus Type 2 Major Capsid Protein Expression
Taejung Kim, Nguyen Tat Toan, Jayoung Seo, Bockgie Jung, Jaeil Lee and Bongjoo Lee
Porcine circovirus type 2 (PCV2) infections cause important respiratory diseases in the pig industry and are associated with many bacterial, mycoplasmal, and viral complications. In this study, a heterologous PCV2 major capsid protein (MCP) was expressed...









