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PMWS Research Archives
Published Nov 2005: Arch Virol.Genetic characterization of type 2 porcine circoviruses detected in Hungarian wild boars.
Csagola A, Kecskemeti S, Kardos G, Kiss I, Tuboly T.
Porcine circoviruses (PCV) are present in pigs worldwide; they are grouped into two types: PCV1 comprising non-pathogenic viruses and PCV2 responsible for several clinical manifestations. Both types are frequently detected in domestic pigs, the prevalence...
Published Nov 2005: Xenotransplantation Volume 12 Issue 6 Page 465 -
Ultrastructural alterations in human blood leukocytes induced by porcine circovirus type 1 infection
Gabriel Arteaga-Troncoso, Fernando Guerra-Infante, Luz Maria Rosales-Montaño, Francisco Javier Díaz-García and Saúl Flores-Medina
Background: Swine infectious pathogens, especially viruses, represent a potential public health risk associated with the use of pig tissues for xenotransplantation in humans. We hypothesized that porcine circovirus type I (PCV-1) may infect human...
Published Nov 2005: J Interferon Cytokine Res. - 25(11):684-93
Enhancement of porcine circovirus 2 replication in porcine cell lines by IFN-gamma before and after treatment and by IFN-alpha after treatment.
Meerts P, Misinzo G, Nauwynck HJ.
Stimulation of the porcine immune system causes increased replication of porcine circovirus 2 (PCV2) in vivo. In the present study, we investigated whether various cytokines (interleukin-1 [IL-1], IL-6, IL-10, tumor necrosis factor-alpha [TNF-alpha],...
Published Nov 2005: Vet Immunol Immunopathol. 24 -
Immunopathological effects of porcine circovirus type 2 (PCV2) on swine alveolar macrophages by in vitro inoculation.
Chang HW, Jeng CR, Lin TL, Liu JJ, Chiou MT, Tsai YC, Chia MY, Jan TR, Pang VF.
Porcine circovirus type 2 (PCV2) is the primary causative agent of postweaning multisystemic wasting syndrome (PMWS), a multifactorial disease, in pigs. Monocyte/macrophage lineage cells, including alveolar macrophages (AMs), are the major target cells...
Published Nov 2005: Clin Diagn Lab Immunol. - 12(11):1347-51. -
Effects of porcine circovirus type 2 (PCV2) maternal antibodies on experimental infection of piglets with PCV2.
McKeown NE, Opriessnig T, Thomas P, Guenette DK, Elvinger F, Fenaux M, Halbur PG, Meng XJ.
To determine the effects of porcine circovirus type 2 (PCV2) maternal antibodies on and response to experimental PCV2 infection, 24 piglets were divided into four groups on the basis of the enzyme-linked immunosorbent assay titers of PCV2 maternal antibodies:...
Published Nov 2005: Veterinary Microbiology, In Press, Corrected Proof,
Quantification of porcine circovirus type 2 (PCV2) DNA in serum and tonsillar, nasal, tracheo-bronchial, urinary and faecal swabs of pigs with and without postweaning multisystemic wasting syndrome (PMWS)
J. Segalés, M. Calsamiglia, A. Olvera, M. Sibila, L. Badiella and M. Domingo
The present study focused on PCV2 quantification by TaqMan PCR in nasal (n = 99), tonsillar (n = 108), tracheo-bronchial (n = 72), urinary (n = 91) and faecal (n = 42) swabs, as well as in serum (n = 57), from...
Published Nov 2005: Pig Journal Volume: 56 -
Post-weaning Multisystemic Wasting Syndrome (PMWS) in Denmark - The situation to date
P. Baekbo
Post-wasting Multisystemic Wasting Syndrome (PMWS) was first diagnosed in Denmark in 2000. In April 2005, Denmark had 541 confirmed cases of PMWS. This corresponds to a prevalence of approximately 10 per cent of all sow herds. However, the estimated...
Published Nov 2005: Pig Journal Volume: 56 -
Postweaning Multisystemic Wasting Syndrome (PMWS) Research in Denmark
P. Baekbo
In Denmark, much research on PMWS takes place in co-operation between the pig industry and public research institutes. Completed studies indicate that PMWS can be transmitted from pig to pig and that low levels of Vitamin E at weaning increase the risk...
Published Nov 2005: Pig Journal Volume: 56 -
Postweaning Multisystemic Wasting Syndrome (PMWS) in purebred wild boar (Sus Scrofa) on a farm in East Anglia
N.G.A. Woodger
Post-weaning multisystemic wasting syndrome (PMWS) was diagnosed in farmed Wild Boar in East Anglia. This involved an overstocked unit, resulting from movement restrictions following the 2001 Foot-and-Mouth disease epidemic. A severe wasting disease...
Published Nov 2005: Pig Journal Volume: 56 -
Post-weaning Multisystemic Wasting Syndrome (PMWS) in Farms: Defining disease and the role of Porcine Circovirus 2 (PCV2)
M. Turner, C. Schnier, K. Woodbine, L. Green, G. Medley and J. Slevin
The cause of PMWS is as yet undetermined. There has been great controversy over the role of PCV2 in the disease. Current case definitions for the disease vary, but all include the presence of PCV2 antigen or nucleic acid. In a cross-sectional study of...
Published Nov 2005: Pig Journal Volume: 56 -
The use of PRACETAM (Paracetamol) premix in Post-weaning Multisystemic Wasting Syndrome (PMWS) and Post-weaning diets
L. Glattleider and N. Capdevielle
Controlled clinical trials were performed to evaluate the effect of PRACETAM in either PMWS or in a post-weaning diet. The efficacy of PRACETAM was demonstrated by a controlled clinical trial under blind conditions in a pig herd chronically infected...
Published Oct 2005: BMC Vet Res. - 31;1:7.
Porcine circovirus type 2 (PCV2) causes apoptosis in experimentally inoculated BALB/c mice.
Kiupel M, Stevenson GW, Galbreath EJ, North A, HogenEsch H, Mittal SK.
BACKGROUND: We have previously described microscopic and electron microscopic alterations in lymphoid organs of PCV2 inoculated mice as apoptosis. In this study we wanted to investigate the molecular pathogenetic mechanism of PCV2-induced apoptosis. Eight-week...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Development of the immune system in the neonatal piglet and its interaction with PCV2 infection.
BAILEY M
The immune system of neonatal piglets undergoes a very rapid and massive development. This drastic expansion seems to be one of the factors that interact with porcine circovirus 2 (PCV2) infection to trigger postweaning multisystemic wasting syndrome...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Vaccination strategies for the control of circoviral diseases in pigs.
CHARREYRE C, BESEME S, BRUN A, BUBLOT M, JOISEL F, LAPOSTOLLE B, SIERRA P, VAGANAY A
Vaccination appears to be the most efficient way of preventing porcine circovirus type 2 (PCV2)-induced diseases in pigs. MERIAL studied the efficacy of a vaccination scheme in sows and their piglets under laboratory conditions. An inactivated oil adjuvanted...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Dynamics of seroconversion to PCV2, PPV and PRRSV in PMWS affected and PMWS free herds in Poland.
PODGORSKA K, STADEJEK T
As it was suggested that porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) were factors contributing to the development of postweaning multisystemic wasting syndrome (PWMS), the seroconversion against porcine circovirus...
