PMWS Research Archives

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Influence of porcine circovirus type 2 (PCV2)-infection on efficacy and safety of a modified live porcine reproductive and respiratory syndrome (PRRSV) vaccine.
OPRIESSNIG T, HALBUR PG
This study aimed at investigating the influence of porcine circovirus type 2 (PCV2) infection on the efficacy of the vaccine against the porcine reproductive and respiratory syndrome virus (PRRSV). Seventy 2-week-old SPF pigs were randomly distributed...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Search for viral triggers on a PMWS affected farm.
McNAIR I, McNEILLY F, LAGAN P, McKAY K, DUFFY C, CAPRIOLI A, ALLAN G
The objective of this study was to search for any factor triggering the pathogenic effect of porcine circovirus type 2 (PCV2). In a farm affected by postweaning multisystemic wasting syndrome (PMWS), 50 conventionally reared piglets were identified at...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Evidence of genetics influence on the expression of porcine circovirus disease (PCVD) in postweaning pigs.
LOPEZ-SORIA S, SEGALES J, NOFRARIAS M, CALSAMIGLIA M, ESPINAL A, RAMIREZ H, MINGUEZ A, SERRANO JM, MARIN O, CALLEN A
The aim of this study was to investigate whether different genetic boar lines could be associated with general and porcine circovirus disease (PCVD) associated postweaning mortality. The study took place in two similar Spanish farms, free from porcine...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Impact of the route on the transfection effectiveness with infectious cloned genomic DNA of type 2 porcine circovirus.
GRASLAND B, BLANCHARD P, OGER A, BIGARRE L, CARIOLET R, JESTIN A
The transfection effectiveness of a cloned porcine circovirus type 2 (PCV2) inoculated by the natural transmission routes of the virus was investigated. Thirty-five specific-pathogen-free piglets (7 weeks old) were randomly divided into 4 groups. All...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Porcine circovirus type 2 blocks immune activation of natural interferon producing cells.
VINCENT IE, SUMMERFIELD A, STEINER E, GUZYLACK-PIRIOU L, McCULLOUGH KC
In vitro tests were conducted in order to assess the effect of porcine circovirus type 2 (PCV2) on the immune activation of natural interferon producing cells (NIPC). The results showed that PCV2 could have negative effects on the immune response of NIPC...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Immunological longitudinal PMWS cohort study.
LAGAN TREGASKIS P, McNEILLY F, McNAIR I, CAPRIOLI A, DUFFY C, ALLAN G
This study aimed at determining whether there was a link between maternal antibodies to PCV2 and the susceptibility of piglets to PMWS. Five sows, about to farrow, from a Northern Ireland pig herd farm, affected by PMWS, were selected for this 3-month...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
PCV2 infection dynamics in two farms: relationship with PMWS expression, mortality and weight.
LOPEZ-SORIA S, SEGALES J, NOFRARIAS M, SIBILA M, ESPINAL A, RAMIREZ H, MINGUEZ A, SERRANO JM, MARIN O, JOISEL F, CHARREYRE C
The aim of this study was to compare the effect of two prorcine circovirus type 2 (PCV2) infection dynamics on postweaning multisystemic wasting syndrome (PMWS). The study took place in two similar Spanish farms, free from porcine reproductive and respiratory...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
A cohort study on time to PCV2 seroconversion in three post-weaning multisystemic wasting syndrome (PMWS) affected farms.
ROSE N, PENHARD A, EVENO E, BLANCHARD P, OGER A, GRASLAND B, JOLLY JP, JESTIN A, MADEC F
The risk of developing a postweaning multisystemic wasting syndrom (PWMS) seems to be higher when porcine circovirus type 2 (PCV2) seroconversion occurs early in the piglet life. This study aimed at identifying the risk factors leading to PCV2 seroconversion...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
An epidemiological case-control study of post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) in pigs in The Netherlands.
DE JONG MF, WELLENBERG GJ, ELBERS ARW
A case-control study, aiming at knowing better the protential risk factors for postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS), was carried out with pigs affected or not by PMWS and PDNS. Potential...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Porcine circovirus type 2: enzyme-linked immunosorbent assay (ELISA) for the detection of antigen and antibodies in feces.
LOPEZ P, GUILLOSSOU S, DESHAIES E, BRAJON N, BESTUL K, LETERME S
The usual methods used to detect the presence of porcine circovirus type 2 (PCV2) in pigs have their limits. Two Enzyme-Linked Immunosorbent Assay (ELISA) tests were developed: an antibody-detection blocking ELISA and an anitgen-detection capture ELISA....

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Benefit of PCV2 serological and genomic load profiles on PMWS diagnosis in field cases.
BLANCHARD P, ROSE N, GRASLAND B, OGER A, EVENO E, MADEC F, JESTIN A
This study aimed at assessing the serological profile and the genomic load profile in porcine circovirus type 2 (PCV2) infection. The study was carried out in 3 farms affected by postweaning multisystemic wasting sndrome (PMWS), in which pregant sows...

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Porcine circovirus type 2 enteritis is an important differential diagnosis to porcine proliferative enteropathy caused by Lawsonia intracellularis.
JENSEN TK, VIGRE H, SVENSMARK B, LARSEN LE, BILLE-HANSEN V
Similar symptoms can be observed during Lawsonia intracellularis and porcine circovirus type 2 (PCV2) infections. This study aimed at determining whether PCV2 infection was a significant differential diagnosis to L. intracellularis infection....

Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Protection of piglets against a PCV2 experimental challenge by vaccinating gilts with an inactivated adjuvanted PCV2 vaccine.
CHARREYRE C, BESEME S, BRUN A, BUBLOT M, LAPOSTOLLE B , SIERRA P, VAGANAY A
The efficacy of an inactivated oil adjuvanted porcine circovirus type 2 (PCV2) vaccine (CIRCOVAC®) was studied. Twenty-two specific pathogen free gilts, seronegative for PCV2, were randomly divided into 2 groups. Gilts form Group 1 were vaccinated with...

Published Sep 2005: Dtsch Tierarztl Wochenschr. - 112(9):348-51.
Prevalence and association of porcine circovirus type 2 (PCV2), porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) in aborted fetuses, mummified fetuses, stillborn and nonviable neonatal piglets
Ritzmann M, Wilhelm S, Zimmermann P, Etschmann B, Bogner KH, Selbitz HJ, Heinritzi K, Truyen U.
Porcine circovirus type 2 (PCV2) seems to cause reproductive failure in sows not only in experimental studies. A retrospective study was made with a total of 252 aborted fetuses, mummified fetuses, stillborn and nonviable neonatal piglets to determine...

Published Sep 2005: Vet Microbiol - 30;110(1-2):141-6.
Genotyping of porcine circovirus type 2 from a variety of clinical conditions in China.
Wen L, Guo X, Yang H.
Genotypes of porcine circovirus type 2 (PCV2) in clinical tissue specimens collected from pigs of different region in China between 2001 and 2003 were analyzed by PCR and restriction fragment length polymorphism (RFLP) analysis of PCV2 genomic DNA encompassing...

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