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PMWS Research Archives
Published Nov 2004: Pig Journal Volume: 54 -The effect of passive colostral transfer on the subsequent viability and development of post-weaning multisystemic wasting syndrome (PMWS) in piglets
A. Moll
The importance of colostrum is easily overlooked in modern pig units. This paper describes an on-farm project carried out to confirm its significance. The test group consisted of a hundred 24-48h old piglets from 10 sows. The ensuing study took in...
Published Nov 2004: J. Gen. Virol., 85: 3377 - 3382.
Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product
M. Fenaux, T. Opriessnig, P. G. Halbur, Y. Xu, B. Potts and X.-J. Meng
Non-pathogenic porcine circovirus type 1 (PCV1) and pathogenic PCV2 are widespread in swine herds. In this study, the detection and characterization of PCV1 and PCV2 DNA from porcine-derived commercial pepsin are reported. The complete genomic sequences...
Published Nov 2004: Veterinary Record, 2004, Volume 155, Nº19, 597-598
Distribution of PCV2 DNA in the reproductive tract, oocytes and embryos of PCV2 antibody-positive pigs.
BIELANSKI A, LAROCHELLE R, ALGIRE J, MAGAR R
The distribution of PCV2 DNA in the reproductive tract of PCV2 antibody positive gilts was investigated. In addition, 120 embryos were collected from 6 PCV2-antibody positive sows slaughtered 6 days after breeding and submitted to PCV2 DNA detection as...
Published Oct 2004: Veterinary Record, 2004, Volume 155, Nº16, 489-492
Prevalence of porcine circovirus type 2 in aborted fetuses and stillborn piglets.
KIM J, JUNG K, CHAE, C
The 350 aborted fetuses and stillborn piglets included in this study originated from farms in which neither PMWS or PDNS were observed. A screening for the presence of porcine parvovirus (PPV), porcine reproductive and respiratory syndrome virus (PRRSV)...
Published Oct 2004: Veterinary Record, 2004, Volume 155, Nº16, 504
Genetic influence on the expression of PCV disease [letter].
LOPEZ-SORIA S, SEGALES J, NOFRARIAS M, CALSAMIGLIA M, RAMIREZ H, MINGUEZ A, SARRANO JM, MARIN O, CALLEN A
Three paternal genetic lines were used to inseminate sows in two farms (N1 and N2) of a multisite production system. All piglets born of these sows were monitored for mortality from 3 to 21 weeks of age. Post-mortem examination was carried out on each...
Published Oct 2004: Schweiz Arch Tierheilkd. 2004 Oct;146(10):461-8; discussion 469.(Abstract)
Porcine circovirus as a possible cause of postweaning wasting in pigs in Switzerland.
Staebler S, Buergi E, Litzenberger B, McCullough K, McNair I, McNeilly F, Pospischil A, Sydler T. - Institute of Veterinary Pathology, University of Zurich, Switzerland.
Postweaning wasting is a major worldwide problem in pig production, particularly with respect to the disease termed postweaning multisystemic wasting syndrome (PMWS). In addition to wasting, PMWS symptoms include respiratory distress, diarrhoea, pallor...
Published Oct 2004: J Gen Virol Oct 2004; 85: 2837 - 2844.
Apoptosis in lymphoid organs of pigs naturally infected by porcine circovirus type 2
Ana R. Resendes, Natàlia Majó, Joaquim Segalés, Enric Mateu, Maria Calsamiglia and Mariano Domingo - Departament de Sanitat i d'Anatomia Animals and Centre de Recerca en Sanitat Animal (CReSA), Universitat Autònoma de Barcelona, 08193 Bellaterra (Barcelona), Spain
The objective of the present study was to evaluate the involvement of apoptosis in the development of post-weaning multisystemic wasting syndrome (PMWS) lymphoid-depletion lesions. Twenty-one pigs that were categorized into three different lesional severity...
Published Sep 2004: Vet Pathol. 41(5):471-81.
Features of Cell Degeneration and Death in Hepatic Failure and Systemic Lymphoid Depletion Characteristic of Porcine Circovirus-2-associated Postweaning Multisystemic Wasting Disease.
Krakowka S, Ellis J, McNeilly F, Meehan B, Oglesbee M, Alldinger S, Allan G. - Goss Laboratory, Ohio State University, 1925 Coffey Road, Columbus, OH 43210 (USA).
Tissue section replicates from lymphoid tissues and livers of gnotobiotic swine were examined by immunohistochemistry for the colocalization of porcine circovirus-2 (PCV-2) nucleocapsid and terminal deoxynucleotidyl transferase (TdT)-mediated incorporation...
Published Sep 2004: Rev Argent Microbiol. 2004 Jul-Sep;36(3):118-24.
Pathological findings in pigs affected by the postweaning multisystemic wasting syndrome in Argentina
Sarradell J, Perez AM, Comba E, Pereira N, Anthony L, Andrada M, Segales J.
(Article in Spanish) Postweaning multisystemic wasting syndrome was first described in Canada in 1991 and at present an increasing number of cases has been diagnosed worldwide. In Argentina the first cases of PMWS were reported recently. Forty eight...
Published Sep 2004: Journal of Comparative Pathology - August-October 2004 Volume 131, Issues 2-3, Pages 121-126
Expression of Monocyte Chemoattractant Protein-1 and Macrophage Inflammatory Protein-1 in Porcine Circovirus 2-induced Granulomatous Inflammation
J. Kim and C. Chae - Department of Veterinary Pathology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, San 56-1, Shillim-Dong, Kwanak-Gu 141-742, Seoul, South Korea
The expression of monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1 (MIP-1) in granulomatous inflammation of lymph nodes was determined in 1-day-old piglets inoculated intranasally with porcine circovirus 2 (PCV2). The methods...
Published Aug 2004: Journal of Virology, August 2004, p. 8135-8145, Vol. 78, No. 15
Epitope Mapping of the Major Capsid Protein of Type 2 Porcine Circovirus (PCV2) by Using Chimeric PCV1 and PCV2
Porntippa Lekcharoensuk, Igor Morozov, Prem S. Paul, Nattarat Thangthumniyom, Worawidh Wajjawalku, and X. J. Meng
Type 2 porcine circovirus (PCV2) is associated with postweaning multisystemic wasting syndrome in pigs, whereas the genetically related type 1 PCV (PCV1) is nonpathogenic. In this study, seven monoclonal antibodies (MAbs) against PCV2-ORF2 capsid protein...
Published Jul 2004: Research in Veterinary Science 2004 Oct;77(2):171-5.
Detection and genetic characterization of porcine circovirus type 2 (PCV2) in pigs from Croatia.
Jemersic L, Cvetnic Z, Toplak I, Spicic S, Grom J, Barlic-Maganja D, Terzic S, Hostnik P, Lojkic M, Humski A, Habrun B, Krt B. - Virology Department, Croatian Veterinary Institute, Savska cesta 143, 10000 Zagreb, Croatia.
Porcine circovirus type 2 (PCV2) from the Circoviridae family has recently been associated with two serious diseases of swine, post-weaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). During 2002, several...
Published Jul 2004: Research in Veterinary Science 2004 Oct;77(2):177-84.
The presence of co-infections in pigs with clinical signs of PMWS in The Netherlands: a case-control study.
Wellenberg GJ, Stockhofe-Zurwieden N, Boersma WJ, De Jong MF, Elbers AR. - Division of Infectious Diseases, Animal Sciences Group (ID-Lelystad), Edelhertweg 15, P.O. Box 65, 8200 AB, Lelystad, The Netherlands.
In this study, 60 pigs with clinical signs of post-weaning multisystemic wasting syndrome (PMWS) from 20 different pig herds and 180 control pigs (without clinical signs of PMWS) were examined to get more insights into the frequencies of porcine circovirus...
Published Jul 2004: Vet Journal. 168(1):41-9.(Abstract)
Postweaning multisystemic wasting syndrome: a review of aetiology, diagnosis and pathology.
Chae C. - Department of Veterinary Pathology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, San 56-1, Shillim-dong, Kwanak-Gu 151-742, Seoul, South Korea.
This review paper concentrates on the aetiology, diagnosis, and pathological aspects of postweaning multisystemic wasting syndrome (PMWS). PMWS was first recognized in Canada in 1996 as a new emerging disease which caused wasting in postweaned pigs. Since...
Published Jul 2004: 18th IPVS Congress, Hamburg, Germany, June 27- July 2, 2004 - Volume 1:12
Evaluation of differences in host susceptibility to PCV2-associated disease
Opriessnig T, Anderson MS, Rothschild MF, Evans RB, Fenaux M, Meng XJ, Halbur PG
Duroc, Landrace, and Large White pigs were inoculated with PCV2 at 5-7 weeks of age in order to compare the impact of PCV2 infection on each breed. The comparison was based on clinical signs and severity of gross and microscopic lesions. Landrace pigs...














