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PMWS Research Archives
Published Nov 2005: Pig Journal Volume: 56 -Post-weaning Multisystemic Wasting Syndrome (PMWS) in Denmark - The situation to date
P. Baekbo
Post-wasting Multisystemic Wasting Syndrome (PMWS) was first diagnosed in Denmark in 2000. In April 2005, Denmark had 541 confirmed cases of PMWS. This corresponds to a prevalence of approximately 10 per cent of all sow herds. However, the estimated...
Published Nov 2005: Pig Journal Volume: 56 -
Postweaning Multisystemic Wasting Syndrome (PMWS) Research in Denmark
P. Baekbo
In Denmark, much research on PMWS takes place in co-operation between the pig industry and public research institutes. Completed studies indicate that PMWS can be transmitted from pig to pig and that low levels of Vitamin E at weaning increase the risk...
Published Nov 2005: Pig Journal Volume: 56 -
Postweaning Multisystemic Wasting Syndrome (PMWS) in purebred wild boar (Sus Scrofa) on a farm in East Anglia
N.G.A. Woodger
Post-weaning multisystemic wasting syndrome (PMWS) was diagnosed in farmed Wild Boar in East Anglia. This involved an overstocked unit, resulting from movement restrictions following the 2001 Foot-and-Mouth disease epidemic. A severe wasting disease...
Published Nov 2005: Pig Journal Volume: 56 -
Post-weaning Multisystemic Wasting Syndrome (PMWS) in Farms: Defining disease and the role of Porcine Circovirus 2 (PCV2)
M. Turner, C. Schnier, K. Woodbine, L. Green, G. Medley and J. Slevin
The cause of PMWS is as yet undetermined. There has been great controversy over the role of PCV2 in the disease. Current case definitions for the disease vary, but all include the presence of PCV2 antigen or nucleic acid. In a cross-sectional study of...
Published Nov 2005: Pig Journal Volume: 56 -
The use of PRACETAM (Paracetamol) premix in Post-weaning Multisystemic Wasting Syndrome (PMWS) and Post-weaning diets
L. Glattleider and N. Capdevielle
Controlled clinical trials were performed to evaluate the effect of PRACETAM in either PMWS or in a post-weaning diet. The efficacy of PRACETAM was demonstrated by a controlled clinical trial under blind conditions in a pig herd chronically infected...
Published Oct 2005: BMC Vet Res. - 31;1:7.
Porcine circovirus type 2 (PCV2) causes apoptosis in experimentally inoculated BALB/c mice.
Kiupel M, Stevenson GW, Galbreath EJ, North A, HogenEsch H, Mittal SK.
BACKGROUND: We have previously described microscopic and electron microscopic alterations in lymphoid organs of PCV2 inoculated mice as apoptosis. In this study we wanted to investigate the molecular pathogenetic mechanism of PCV2-induced apoptosis. Eight-week...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Development of the immune system in the neonatal piglet and its interaction with PCV2 infection.
BAILEY M
The immune system of neonatal piglets undergoes a very rapid and massive development. This drastic expansion seems to be one of the factors that interact with porcine circovirus 2 (PCV2) infection to trigger postweaning multisystemic wasting syndrome...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Vaccination strategies for the control of circoviral diseases in pigs.
CHARREYRE C, BESEME S, BRUN A, BUBLOT M, JOISEL F, LAPOSTOLLE B, SIERRA P, VAGANAY A
Vaccination appears to be the most efficient way of preventing porcine circovirus type 2 (PCV2)-induced diseases in pigs. MERIAL studied the efficacy of a vaccination scheme in sows and their piglets under laboratory conditions. An inactivated oil adjuvanted...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Dynamics of seroconversion to PCV2, PPV and PRRSV in PMWS affected and PMWS free herds in Poland.
PODGORSKA K, STADEJEK T
As it was suggested that porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) were factors contributing to the development of postweaning multisystemic wasting syndrome (PWMS), the seroconversion against porcine circovirus...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Influence of porcine circovirus type 2 (PCV2)-infection on efficacy and safety of a modified live porcine reproductive and respiratory syndrome (PRRSV) vaccine.
OPRIESSNIG T, HALBUR PG
This study aimed at investigating the influence of porcine circovirus type 2 (PCV2) infection on the efficacy of the vaccine against the porcine reproductive and respiratory syndrome virus (PRRSV). Seventy 2-week-old SPF pigs were randomly distributed...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Search for viral triggers on a PMWS affected farm.
McNAIR I, McNEILLY F, LAGAN P, McKAY K, DUFFY C, CAPRIOLI A, ALLAN G
The objective of this study was to search for any factor triggering the pathogenic effect of porcine circovirus type 2 (PCV2). In a farm affected by postweaning multisystemic wasting syndrome (PMWS), 50 conventionally reared piglets were identified at...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Evidence of genetics influence on the expression of porcine circovirus disease (PCVD) in postweaning pigs.
LOPEZ-SORIA S, SEGALES J, NOFRARIAS M, CALSAMIGLIA M, ESPINAL A, RAMIREZ H, MINGUEZ A, SERRANO JM, MARIN O, CALLEN A
The aim of this study was to investigate whether different genetic boar lines could be associated with general and porcine circovirus disease (PCVD) associated postweaning mortality. The study took place in two similar Spanish farms, free from porcine...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Impact of the route on the transfection effectiveness with infectious cloned genomic DNA of type 2 porcine circovirus.
GRASLAND B, BLANCHARD P, OGER A, BIGARRE L, CARIOLET R, JESTIN A
The transfection effectiveness of a cloned porcine circovirus type 2 (PCV2) inoculated by the natural transmission routes of the virus was investigated. Thirty-five specific-pathogen-free piglets (7 weeks old) were randomly divided into 4 groups. All...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Porcine circovirus type 2 blocks immune activation of natural interferon producing cells.
VINCENT IE, SUMMERFIELD A, STEINER E, GUZYLACK-PIRIOU L, McCULLOUGH KC
In vitro tests were conducted in order to assess the effect of porcine circovirus type 2 (PCV2) on the immune activation of natural interferon producing cells (NIPC). The results showed that PCV2 could have negative effects on the immune response of NIPC...
Published Sep 2005: International Conference on Animal Circoviruses and Associated Diseases, European Society for Veterinary Virology
Immunological longitudinal PMWS cohort study.
LAGAN TREGASKIS P, McNEILLY F, McNAIR I, CAPRIOLI A, DUFFY C, ALLAN G
This study aimed at determining whether there was a link between maternal antibodies to PCV2 and the susceptibility of piglets to PMWS. Five sows, about to farrow, from a Northern Ireland pig herd farm, affected by PMWS, were selected for this 3-month...
