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PMWS Research Archives
Published Jul 2004: 18th IPVS Congress, Hamburg, Germany, June 27- July 2, 2004 - Volume 1:96Effect of timing of vaccination with commercially available bacterin on PCV2-associated lesions
Opriessnig PT, Meng XJ, Halbur PG
The use of vaccines against Mycoplasma hyopneumoniae has already been demonstrated to enhance the clinical and histopathological impact of PCV2 infection. This experiment was designed so as to compare the effect of different timings of vaccination with...
Published Jul 2004: 18th IPVS Congress, Hamburg, Germany, June 27- July 2, 2004 - Volume 2:807
Studies concerning PMWS rapid diagnostic tools and epidemiology
Calsamiglia M
PCV2 genome amplification and quantification was carried out in nasal, bronchial, tonsillar, fecal and urinary swabs and blood samples from 142 pigs sent to the Veterinary Diagnostic Service at the Universitat Autònoma de Barcelona with various clinical...
Published Jul 2004: 18th IPVS Congress, Hamburg, Germany, June 27- July 2, 2004 - Volume 2:809
Does genetics or litter effects influence mortality in PMWS?
Armstrong D, Bishop SC
This study was based on the data collected in a sow commercial farrow-to-finish farm experiencing a PMWS outbreak. The data regarded 16278 piglets weaned piglets in 1637 litters over an almost 3-year period. Piglet mortality due to PMWS was found significantly...
Published Jun 2004: Journal of Virology, June 2004, p. 6297-6303, Vol. 78, No. 12
A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs
M. Fenaux, T. Opriessnig, P. G. Halbur, F. Elvinger and X. J. Meng
Porcine circovirus type 2 (PCV2) is associated with postweaning multisystemic wasting syndrome in pigs, whereas PCV1 is nonpathogenic. We previously demonstrated that a chimeric PCV1-2 virus (with the immunogenic capsid gene of PCV2 cloned into the backbone...
Published Jun 2004: Archives of Virology - Volume 149, Number 6, Pages: 1171 - 1183
Detection and genetic typing of type 2 porcine circoviruses in archived pig tissues from the UK
S. S. Grierson, D. P. King, T. Sandvik, D. Hicks, Y. Spencer, T. W. Drew1 and M. Banks
Summary. Porcine circovirus 2 (PCV-2) is implicated as the causative agent of post-weaning multisystemic wasting syndrome (PMWS) and is also associated with porcine dermatitis and nephropathy syndrome (PDNS). The recent emergence of epidemic PMWS...
Published Jun 2004: Vet Res.35(3):275-82
Haptoglobin and pig-major acute protein are increased in pigs with postweaning multisystemic wasting syndrome (PMWS).
Segales J, Pineiro C, Lampreave F, Nofrarias M, Mateu E, Calsamiglia M, Andres M, Morales J, Pineiro M, Domingo M. - Centre de Recerca en Sanitat Animal (CReSA), Departament de Sanitat i d'Anatomia Animals, Facultat de Veterinaria, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
The objective of this study was to determine the serum concentration levels of selected acute phase proteins (APP), haptoglobin (HPT) and pig-major acute phase protein (pig-MAP), in postweaning multisystemic wasting syndrome (PMWS) affected pigs and PCV2-subclinically...
Published May 2004: J Vet Med Sci. 2004 May;66(5):469-75.
Characterization of porcine circovirus type 2 in Taiwan.
Wang C, Huang TS, Huang CC, Tu C, Jong MH, Lin SY, Lai SS. - Department of Hog Cholera Research, National Institute for Animal Health, Council of Agriculture, Taipei, Taiwan.
In an effort to understand the genetic diversity of porcine circovirus type 2 (PCV2) and the prevalence of PCV2 infection in Taiwanese herds, we have sequenced the complete genomes from PCV2-infected specimens and individually measured the antibody titer...
Published May 2004: J Vet Med Science - 66(5):533-7
Postweaning multisystemic wasting syndrome (PMWS) in the Philippines: porcine circovirus type 2 (PCV2) detection and characterization.
Maldonado J, Segales J, Calsamiglia M, Llopart D, Sibila M, Lapus Z, Riera P, Artigas C.
Laboratorios Hipra, S.A., Girona, Spain. Four swine facilities located in Northern Luzon, in the Philippines, showed lesions and clinical signs similar to those described in post weaning multisystemic wasting syndrome (PMWS). Post-mortem and histopathological...
Published May 2004: J Vet Diagn Invest. 2004 May;16(3):175-85.
Characteristics of porcine circovirus-2 replication in lymphoid organs of pigs inoculated in late gestation or postnatally and possible relation to clinical and pathological outcome of infection.
Sanchez RE Jr, Meerts P, Nauwynck HJ, Ellis JA, Pensaert MB. - Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Both late-term fetuses in utero and one-day-old cesarean derived piglets were inoculated with PCV2 in an attempt to reproduce PMWS and PMWS-like lesions. Piglets were either euthanized immediately at harvest or sacrificed sequentially and monitored for...
Published May 2004: Vet Immunol Immunopathol, 99(1-2):63-71
Systemic cytokine profile in feeder pigs suffering from natural postweaning multisystemic wasting syndrome (PMWS) as determined by semiquantitative RT-PCR and flow cytometric intracellular cytokine detection.
Sipos W, Duvigneau JC, Willheim M, Schilcher F, Hartl RT, Hofbauer G, Exel B, Pietschmann P, Schmoll F. - II. Medical Clinic for Ruminants and Swine, University of Veterinary Medicine Vienna, Veterinarplatz 1, A-1210 Vienna, Austria.
Postweaning multisystemic wasting syndrome (PMWS) is an economically important disease in pigs caused by porcine circovirus type 2 (PCV2). Development of this disease is presumably associated with an impairment of the immune system. We, therefore, investigated...
Published May 2004: Pig Journal Volume: 53 -
European Management Strategies to control Post-weaning multisystemic wasting syndrome (PMWS)
By M. Donadeu, A.E.J. Waddilove and E. Marco
Since Post-weaning multisystemic wasting syndrome (PMWS) was first identified in Europe, different strategies have been used to try to control the disease and its effects, with variable levels of success. There is no single strategy that can claim control...
Published May 2004: Pig Journal Volume: 53
Porcine Circovirus (PCV) Associated Losses in Pregnant Gilts
By C. Mauch and G. Bilkei
Ninety-four Porcine circovirus (PCV) seronegative replacement gilts in mid-pregnancy were transported to 4 PCV seropositive herds. Thirty-one of them showed, within 2 months of entry, the clinical picture of porcine dermatitis and nephropathy syndrome...
Published May 2004: Arch Virol.- 149(5):857-74.
Pathogenesis of postweaning multisystemic wasting syndrome caused by Porcine circovirus 2: an immune riddle.
Darwich L, Segales J, Mateu E. - Departament Sanitat i Anatomia Animals, Universitat Autonoma de Barcelona, Bellaterra, Spain.
Postweaning multisystemic wasting syndrome (PMWS) is a disease of pigs first recognised in North America in 1997 and subsequently reported worldwide that is caused by Porcine circovirus 2 (PCV2), a member of the family Circoviridae. The most consistent...
Published May 2004: J Gen Virol - 85, 1259-1266 -
In vitro and in vivo characterization of an infectious clone of a European strain of porcine circovirus type 2
M. Roca, M. Balasch, J. Segalés, M. Calsamiglia, E. Viaplana, A. Urniza, K. Hattermann, A. Mankertz, J. Plana-Durán and M. Domingo
The aim of this study was to describe the generation of a PCV2 (porcine circovirus type 2) infectious clone (pIC-PCV2) and its infectivity under in vitro and in vivo conditions. The constructed pIC-PCV2 contained the whole PCV2 genome from...
Published May 2004: J Gen Virol - May 2004 - 85, 1259-1266 -
In vitro and in vivo characterization of an infectious clone of a European strain of porcine circovirus type 2
M. Roca, M. Balasch, J. Segalés, M. Calsamiglia, E. Viaplana, A. Urniza, K. Hattermann, A. Mankertz, J. Plana-Durán and M. Domingo
The aim of this study was to describe the generation of a PCV2 (porcine circovirus type 2) infectious clone (pIC-PCV2) and its infectivity under in vitro and in vivo conditions. The constructed pIC-PCV2 ...
